Diseases, Conditions, Syndromes

Mozambique faces alarming multidrug-resistant tuberculosis epidemic

With one of the highest tuberculosis (TB) incidences (368 cases/100,000 population) in the African region, Mozambique is particularly affected by the TB epidemic. Drug-resistant TB is also a major problem, with 4,800 new ...

Medications

New antibiotics could tackle drug-resistant tuberculosis bacteria

Infection by Mycobacterium tuberculosis kills 1.5 million people worldwide every year. Antibiotics to treat TB exist, but in recent years, multi-drug resistant (MDR), extensively drug-resistant (XDR) and totally drug-resistant ...

Medications

Protein contributes to drug tolerance in tuberculosis

Weill Cornell Medicine researchers have identified a protein in Mycobacterium tuberculosis (Mtb) that contributes to drug tolerance, a phenomenon that allows bacteria to survive treatment with drugs that would normally kill ...

Diseases, Conditions, Syndromes

Tuberculosis—Inhibiting host cell death with immunotherapy

Tuberculosis treatment still entails the administration of several antibiotics over a period of months and is torturous for many patients. The pathogen's increasing multidrug resistance additionally complicates this lengthy ...

Diseases, Conditions, Syndromes

Experts develop immune-enhancing therapies to target tuberculosis

Experts are working on novel immune-enhancing therapies called host-directed therapies to use the body's own immune system to target tuberculosis, with hopes that they could tackle even the drug-resistant forms of the disease. ...

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