Oncology & Cancer

How cancer cells escape crowded tumors

Like people, cells in the human body protect their personal space. They seem to know how much space they need, and if it gets too tight, most cells prefer to break free. The mechanism enabling cells to evade crowded environments ...

Genetics

VAV1 gene mutations trigger T-cell tumors in mice

Life is an exquisite orchestration of growth and change, with checks and balances that fine-tune complex entwined interactions, both intrinsic and external. White blood cells (WBC) are integral to an organism's immune defenses ...

Obstetrics & gynaecology

Simple twist of DNA determines fate of placenta

The development of the mammalian placenta depends upon an unusual twist that separates DNA's classic double helix into a single-stranded form, Yale researchers report July 15 in the journal Nature.

Oncology & Cancer

Autophagy genes act as tumor suppressors in ovarian cancer

Shedding light on a decades-old controversy, scientists at the Medical University of South Carolina (MUSC) and University of California at San Diego (UCSD) published findings in PLOS Genetics this month showing that autophagy ...

Medical research

Linking wound healing and cancer risk

When our skin is damaged, a whole set of biological processes springs into action to heal the wound. Now, researchers from the VIB-UGent Center for Inflammation Research have shown that one of the molecules involved in this, ...

Oncology & Cancer

Researchers develop novel immunotherapy to target colorectal cancer

A Yale-led research team has developed an antibody that blocks tumors in animal models of colorectal cancer. If the finding is confirmed in clinical trials, the antibody-based treatment could become an effective weapon against ...

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