Oncology & Cancer

Exposing cancer's metabolic addictions

Cancerous tumors are classified primarily based on their tissue of origin. However, the sequencing of the human genome and the development of powerful and affordable DNA sequencing technologies has ushered in a new era of ...

Genetics

Researchers relate DNA methylation levels to obesity

DNA methylation is a mechanism that regulates whether genes are "on" or "off", and is influenced by hereditary and environmental factors, as well as lifestyle and nutritional habits.

Oncology & Cancer

A hidden route for fatty acids can make cancers resistant to therapy

Fatty acid metabolism is an essential process in tumor growth and proliferation. Despite attempts to block fatty acid metabolism as a therapeutic strategy to reduce tumor size and growth, the outcome has not always been positive. ...

Immunology

Energizing the immune system to eat cancer

Immune cells called macrophages are supposed to serve and protect, but cancer has found ways to put them to sleep. Now researchers at the Abramson Cancer Center of the University of Pennsylvania say they've identified how ...

Oncology & Cancer

Study overturns dogma of cancer metabolism theory

Scientists at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have discovered that squamous cell skin cancers do not require increased glucose to power their development and growth, ...

Medical research

Mapping metabolism with a novel imaging technique

Yale researchers have developed a new imaging technique that captures detailed information about metabolism, which plays a role in many diseases. The novel yet simple technique, which harnesses existing technology, could ...

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