Oncology & Cancer

Research reveals machinery of a deadly childhood brain cancer

St. Jude Children's Research Hospital scientists have mapped the effects of aberrant biological machinery that drives a deadly brain cancer called diffuse intrinsic pontine glioma (DIPG). The research included development ...

Oncology & Cancer

Understanding epilepsy in pediatric tumors

Pediatric brain tumors are characterized by frequent complications due to intractable epilepsy compared to adult brain tumors. However, the genetic cause of refractory epilepsy in pediatric brain cancer has not been elucidated ...

Oncology & Cancer

Researchers unlock secret of deadly brain cancer's 'immortality'

UC San Francisco researchers have discovered how a mutation in a gene regulator called the TERT promoter—the third most common mutation among all human cancers and the most common mutation in the deadly brain cancer glioblastoma—confers ...

Oncology & Cancer

New clues found to understanding relapse in breast cancer

A large genomic analysis has linked certain DNA mutations to a high risk of relapse in estrogen receptor positive breast cancer, while other mutations were associated with better outcomes, according to researchers from Washington ...

Oncology & Cancer

Using AI to make cancer evolution more predictable

A team of researchers affiliated with several institutions in the U.K. and one in the U.S. has developed a way to use artificial intelligence to predict how cancer might change and spread in patients. The results are published ...

Oncology & Cancer

A targeted approach to treating glioma

Glioma, a type of brain cancer, is normally treated by removing as much of the tumor as possible, followed by radiation or chemotherapy. With this treatment, patients survive an average of about 10 years, but the tumors inevitably ...

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