Medical research

Cancer overrides the circadian clock to survive

Tumor cells use the unfolded protein response to alter circadian rhythm, which contributes to more tumor growth, Hollings Cancer Center researchers at the Medical University of South Carolina (MUSC) find. A key part of the ...

Medical research

How cells detect, mend DNA damage may improve chemotherapy

The busy world inside a cell is directed by its DNA blueprint. When the blueprints are altered, cells can sicken, die or become cancerous. To keep DNA in working order, cells have ways to detect and mend damaged DNA.

Health

Inverse association seen for coffee drinking, markers of CVD

(HealthDay)—There appears to be an inverse association between coffee intake and protein markers linked to cardiovascular disease, according to a study published online Oct. 16 in the Journal of Internal Medicine.

Oncology & Cancer

Newly discovered cellular pathway may lead to cancer therapies

Scientists have discovered a new cellular pathway that can promote and support the growth of cancer cells. In a mouse model of melanoma, blocking this pathway resulted in reduction of tumor growth. The study, which appears ...

Oncology & Cancer

Prototype drug uses novel mechanism to treat lung cancers

Cells are constantly turning proteins on and off via molecular switches—phosphate molecules—that have become common drug targets. in a new study, lung cancer tumors were prevented in mice by a novel small molecule that ...

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