Inverse association seen for coffee drinking, markers of CVD

October 24, 2017

(HealthDay)—There appears to be an inverse association between coffee intake and protein markers linked to cardiovascular disease, according to a study published online Oct. 16 in the Journal of Internal Medicine.

Marilyn C. Cornelis, Ph.D., from Northwestern University in Chicago, and colleagues performed an analysis of known and novel linked to and their association with habitual . Initial analysis used dietary records data from the Prospective Study of the Vasculature in Uppsala Seniors (PIVUS; n = 816), and the top proteins were validated using data from the Uppsala Longitudinal Study of Adult Men (ULSAM, n = 635) and EpiHealth (n = 2,418).

The researchers found that after adjustment for age, sex, smoking and body mass index, four protein-coffee associations met statistical significance in PIVUS: leptin (LEP), chitinase-3-like protein 1 (CHI3L), (TNF) receptor 6, and TNF-related apoptosis-inducing ligand. In the two validation sets, a similar inverse association between coffee intake and LEP was found, but the negative coffee-CHI3L association was replicated only in EpiHealth.

"The coffee-CHI3L1 association is novel and warrants further investigation given links between CHI3L1 and health conditions that are also potentially influenced by coffee," the authors write.

One author disclosed financial ties to a proteomics company.

Explore further: Coffee, caffeine not linked to psoriasis in U.S. women

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Coffee, caffeine not linked to psoriasis in U.S. women

March 21, 2012
(HealthDay) -- Coffee and caffeine are not associated with psoriasis incidence after adjustment for smoking, according to a research letter published in the March issue of the Archives of Dermatology.

Caffeine linked to lower risk of death in women with diabetes

September 13, 2017
Women with diabetes who regularly drink caffeinated coffee or tea may live longer than those who don't consume caffeine at all, according to new research being presented at this year's European Association for the Study of ...

Higher coffee consumption associated with lower risk of death

August 28, 2017
Higher coffee consumption is associated with a lower risk of death, according to research presented today at ESC Congress. The observational study in nearly 20 000 participants suggests that coffee can be part of a healthy ...

Inverse link for coffee intake, cholecystectomy risk

June 2, 2015
(HealthDay)—For premenopausal women and those using hormone replacement therapy (HRT), there is an inverse association between coffee consumption and risk of cholecystectomy, according to a study published in the June issue ...

No link for tea, coffee intake with barrett's esophagus

May 5, 2016
(HealthDay)—After adjustment for confounding variables there is no correlation between the risk of Barrett's esophagus (BE) and tea or coffee consumption, according to a study published in the May issue of Clinical Gastroenterology ...

Dietary factors linked to risk of acute pancreatitis

January 30, 2017
(HealthDay)—Dietary factors are associated with pancreatitis, with saturated fat and cholesterol positively linked to gallstone-related acute pancreatitis (AP), according to a study published in the February issue of Clinical ...

Recommended for you

Teen personality traits linked to risk of death from any cause 50 years later

November 20, 2018
Personality traits evident as early as the teenage years may be linked to a heightened or lessened risk of death around 50 years later, suggests observational research of 'baby boomers,' published online in the Journal of ...

One in four U.S. adults sits more than eight hours a day

November 20, 2018
(HealthDay)—Couch Potato Nation: Nearly half of Americans sit for far too many hours a day and don't get any exercise at all, a new study finds.

Emotional abuse may be linked with menopause misery

November 19, 2018
Smoking, obesity and a sedentary lifestyle have long been linked to heightened symptoms of menopause. Now, a study headed by UC San Francisco has identified another factor that may add to menopause torment: an emotionally ...

Bullying and violence at work increases the risk of cardiovascular disease

November 19, 2018
People who are bullied at work or experience violence at work are at higher risk of heart and brain blood vessel problems, including heart attacks and stroke, according to the largest prospective study to investigate the ...

How AI could help veterinarians code their notes

November 19, 2018
A team led by scientists at the School of Medicine has developed an algorithm that can read the typed-out notes from veterinarians and predict specific diseases that the animal may have.

US paves way to get 'lab meat' on plates

November 17, 2018
US authorities on Friday agreed on how to regulate food products cultured from animal cells—paving the way to get so-called "lab meat" on American plates.

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.