Cancer cells have developed multiple mechanisms to thrive. One example, derived from age-old theories of evolution, is positive selection i.e., the propensity of cells with favorable cancer mutations to flourish. However, ...
Jan 18, 2023
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A new research paper titled "Targeting CD74 in B-cell non-Hodgkin lymphoma with the antibody-drug conjugate STRO-001" has been published in Oncotarget.
Jan 17, 2023
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CAR T cell therapy, an approach which reprograms patients' own immune cells to attack their blood cancers, may enhance the effectiveness of surgery for solid tumors, according to a preclinical study from researchers in the ...
Jan 11, 2023
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The great hope of cancer immunotherapy is to bolster our own immune cells in specific ways to keep cancer cells from evading our immune system. Although much progress has been made, immunotherapy does not always work well. ...
Dec 19, 2022
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A team at Memorial Sloan Kettering Cancer Center (MSK) has uncovered several mechanisms of immune escape that can help explain why ovarian cancers have been resistant to immunotherapy to date.
Dec 15, 2022
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Although tumors in the nasal cavity and the paranasal sinus are confined to a small space, they encompass a very broad spectrum with many tumor types. As they often do not exhibit any specific pattern or appearance, they ...
Nov 29, 2022
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In many cancer types, cancer cells try to survive by escaping attack from the immune system. These cancer cells hijack mechanisms called immune checkpoints to trick the immune system into thinking they are healthy cells. ...
Nov 28, 2022
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Duke Cancer Institute researchers have identified potential biomarkers that predict the likelihood for checkpoint inhibitor drugs to backfire, driving hyper-progression of melanoma cells instead of unleashing the immune system ...
Nov 23, 2022
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Scientists at the University of Pittsburgh School of Medicine have discovered the missing puzzle piece in the mystery of how melanoma tumors control their mortality.
Nov 10, 2022
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Bowel cancers can be grouped into six clinically meaningful subtypes based on patterns of gene interactions commonly seen within tumor cells, according to research published today in eLife.
Nov 8, 2022
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