Genetics

Exploring autoimmunity's regulatory roots

Our genome contains vast networks that regulate the activity of protein-coding genes. Variations in this regulatory DNA (which does not encode proteins) may affect both when and how much of a given protein a cell produces. ...

Diabetes

Good long-term limb salvage for diabetic foot patients

(HealthDay) -- For patients with diabetic foot ulcers (DFUs), long-term limb salvage is favorable; however, long-term survival remains poor, particularly for those with peripheral artery disease (PAD) or chronic renal insufficiency, ...

Overweight & Obesity

Does your stomach bacteria protect you from obesity?

The germ Helicobacter pylori is the cause of most stomach ulcers, but new research in Alimentary Pharmacology & Therapeutics suggests that treating the bacteria is linked to weight gain.

Diseases, Conditions, Syndromes

'Early warning' tool for hard-to-heal leg wounds

Some 500,000 Australians live with the daily burden of a wound that does not heal, but a risk assessment tool that provides an 'early warning' of which venous leg ulcer wounds need specialised treatment has been developed ...

Diseases, Conditions, Syndromes

Opening up new pathways for treating inflammatory bowel diseases

Inflammatory bowel disease (IBD) is a chronic condition affecting 1 in 250 people in Europe. Current treatment is ineffective for many. However, a team of European scientists has increased understanding of the causes of IBD, ...

Diabetes

Correlates of diabetic foot complications identified

(HealthDay) -- For patients with diabetes, increased poly(ADP-ribose) (PAR) immunoreactivity, reduced abundance of type 1 procollagen, and impaired skin structure correlate with foot complications, according to a study published ...

Diseases, Conditions, Syndromes

Probiotics effective in combating antibiotic-associated diarrhea

In four different studies presented at the American College of Gastroenterology's (ACG) 76th Annual Scientific meeting in Washington, DC, researchers explored the effectiveness of probiotics for antibiotic-associated diarrhea; ...

Immunology

Researchers map the immunology of the gut in children with IBD

Researchers from Karolinska Institutet and Sachs' Children and Youth Hospital have mapped the immune system in the gut of children with inflammatory bowel disease (IBD). The results, which were published in Cell Reports Medicine, ...

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