Cardiology

Ca2+, the intercellular signal in arterioles

Vasoconstriction must be balanced with vasodilation, particularly in the arterioles that supply tissues with blood. Endothelial cells protrude through holes in the internal elastic lamina in arterioles to make contact with ...

Ophthalmology

Reproducing a retinal disease on a chip

Approximately 80% of all sensory input is received via the eyes, so suffering from chronic retinal diseases that lead to blindness causes a significant decrease in the quality of life (QOL). And because retinal diseases are ...

Medical research

Epigenetic program leading to vessel differentiation

Clarification of how human blood vessels are constructed is desperately needed to advance regenerative medicine. A collaborative research group from Kumamoto University, Kyoto University, and the University of Tokyo in Japan ...

Diabetes

RUNX1 may play role in proliferative diabetic retinopathy

(HealthDay)—The Runt-related transcription factor 1 (RUNX1) gene may play a role in human proliferative diabetic retinopathy (PDR), and upregulation may be a marker of aberrant retinal angiogenesis, according to a study ...

Cardiology

Hot flashes could signal increased risk of heart disease

Hot flashes, one of the most common symptoms of menopause, have already been shown to interfere with a woman's overall quality of life. A new study shows that, particularly for younger midlife women (age 40-53 years), frequent ...

Medical research

Study points to possible treatment for a rare vascular disease

In individuals with a rare genetic disorder that affects blood vessels, arteries and veins develop abnormal connections, causing bleeding in the skin, nose, and other organs. In most cases, the condition—hereditary hemorraghic ...

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