Genetics

Key regulator of COVID viral receptor may be new drug target

Entry of the SARS-CoV-2 virus into human tissues depends on the activity of a host gene that regulates production of a key viral receptor, according to a study publishing June 13 in the open access journal PLOS Biology by ...

Neuroscience

Astrocyte dysfunction found to cause cognitive decline

People with dementia have protein build-up in astrocytes that may trigger abnormal antiviral activity and memory loss, according to a preclinical study by a team of Weill Cornell Medicine investigators.

Alzheimer's disease & dementia

Inflammatory trigger a new clue in Alzheimer's

Scientists from The University of Texas Health Science Center at San Antonio (UT Health San Antonio) today reported that an inflammatory trigger like one present during viral infections is elevated in Alzheimer's disease ...

Cardiology

New viral vectors for targeted gene therapy of heart muscle cells

Gene therapies aim to cure severe, barely treatable monogentic diseases caused by a defect in a single gene. Medical hopes are correspondingly high. Some gene therapies have already been approved in Europe—for example, ...

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