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Top news stories for the week 18

Monday, Apr 29

After 25 years, researchers uncover genetic cause of rare neurological disease

Some families call it a trial of faith. Others just call it a curse. The progressive neurological disease known as spinocerebellar ataxia 4 (SCA4) is a rare condition, but its effects on patients and their families can be ...

Apr 29, 2024

0

198

Healthy lifestyle may offset effects of life-shortening genes by more than 60%

A healthy lifestyle may offset the effects of life-shortening genes by more than 60%, suggests an analysis of the findings from several large long-term studies, published online in the journal BMJ Evidence-Based Medicine.

Apr 29, 2024

0

134

Study suggests that stevia is the most brain-compatible sugar substitute

Given the known risks of consuming high amounts of sugar, today many people are looking for alternative sweeteners that produce a similar taste without prompting significant weight gain and causing other health issues. While ...

Apr 29, 2024 feature

1

100

Researchers from Denmark and Germany find brown fat's 'off-switch'

Brown fat, also known as brown adipose tissue (BAT), is a type of fat in our bodies that's different from the white fat around our belly and thighs that we are more familiar with. Brown fat has a special job—it helps to ...

Apr 29, 2024

0

90

Laws requiring doctors to report a dementia diagnosis to the DMV may backfire

Some states require that physicians report a diagnosis of dementia, including Alzheimer's disease, to the DMV. A new study suggests these mandates may have unintended consequences.

Apr 29, 2024

1

85

Researchers discover enzymes that open new path to universal donor blood

The quest to develop universal donor blood has taken a decisive step forward. Researchers at DTU and Lund University have discovered enzymes that, when mixed with red blood cells, are able to remove specific sugars that make ...

Apr 29, 2024

0

70

Scientists discover key bacterium that maintains protective intestinal mucus barrier under low-fiber diet

A low-fiber "Western diet" causes damage to the protective mucus barrier in the gut, and such damage can increase the risk of inflammation and infection. By studying the gut bacteria of people who increased their intake of ...

Apr 29, 2024

0

66

Tuesday, Apr 30

A better COVID treatment for the immunocompromised? Researchers create a non-toxic potential alternative to Paxlovid

A combination of two antiviral compounds may be a promising alternative to Paxlovid when treating COVID-19 in immunocompromised patients, according to Karen S. Anderson, Ph.D., professor of pharmacology and of molecular biophysics ...

Apr 30, 2024

0

121

Cranberry extracts could boost microbiota and counter cardiometabolic diseases

Cranberry extracts appear to improve intestinal microbiota and help prevent chronic diseases such as diabetes and cardiovascular diseases. A recent study by Université Laval and the Institute of Nutrition and Functional ...

Apr 30, 2024

0

114

Exploring the origins of excitatory and inhibitory neuronal tuning in the postsubiculum

Brain cells can be broadly divided into two categories: inhibitory and excitatory neurons. Excitatory neurons are cells that support the generation of electrical impulses in postsynaptic neurons, thus prompting the activation ...

Apr 30, 2024 feature

0

80

Researchers reveal a new approach for treating degenerative diseases

Proteins are the workhorses of life. Organisms use them as building blocks, receptors, processors, couriers and catalysts. A protein's structure is critical to its function. Malformed proteins not only fail to carry out their ...

Apr 30, 2024

0

66

Neuroscientists find integrity of white brain matter in superagers does not deteriorate, explains sharp memory

A team of neuroscientists from Universidad Politécnica de Madrid and Queen Sofia Foundation Alzheimer Center, both in Spain, has found that so-called superagers maintain memory as they grow older because they do not experience ...

Apr 30, 2024 report

0

65

Study finds some people have a uniquely human gene that enhances immune function

University at Buffalo researchers have found that the active form of a gene promotes a broad range of protective traits. The gene is found in 75% of the population and is known to protect against neurodegeneration. Now, UB ...

Apr 30, 2024

0

59

Scientists find cancer-like features in atherosclerosis, spurring opportunity for new treatment approaches

Researchers have discovered that the smooth muscle cells that line the arteries of people with atherosclerosis can change into new cell types and develop traits similar to cancer that worsen the disease. The study has been ...

Apr 30, 2024

0

55

Wednesday, May 01

New mRNA cancer vaccine triggers fierce immune response to fight malignant brain tumor

In a first-ever human clinical trial of four adult patients, an mRNA cancer vaccine developed at the University of Florida quickly reprogrammed the immune system to attack glioblastoma, the most aggressive and lethal brain ...

May 1, 2024

0

619

Brain imaging study reveals connections critical to human consciousness

In a paper titled, "Multimodal MRI reveals brainstem connections that sustain wakefulness in human consciousness," published in Science Translational Medicine, a group of researchers at Massachusetts General Hospital and ...

May 1, 2024

1

200

New study supports psilocybin's potential as an antidepressant

Psilocybin—the active ingredient in "magic" mushrooms—is a more effective treatment for symptoms of depression than controls, providing further support for its potential as an antidepressant, suggests a study published ...

May 1, 2024

0

147

Researchers find difference in pancreatic cancer cells, offering new hope for immunotherapy effectiveness

A new study has found that pancreatic cancer cells are different based on their location in the pancreas, providing new information about tumors that could lead to better targeted treatments.

May 1, 2024

0

75

First effective treatment found for spitting cobra snakebite

Scientists have discovered a new snakebite treatment to prevent the devastating tissue damage caused by African spitting cobra venom.

May 1, 2024

0

63

Patients with rheumatoid arthritis have unique and complex autoantibody patterns, study reveals

Patients with rheumatoid arthritis (RA) all have a unique and diverse set of antibodies that are involved in the development of the disease. Researchers at Utrecht University unveiled the complexity of these antibodies using ...

May 1, 2024

0

60

Scientists identify new brain circuit in mice that controls body's inflammatory reactions

The brain can direct the immune system to an unexpected degree, capable of detecting, ramping up and tamping down inflammation, shows a new study in mice from researchers at Columbia's Zuckerman Institute.

May 1, 2024

0

55

Thursday, May 02

Study finds metformin reduces COVID-19 viral load, viral rebound

A team of University of Minnesota researchers found that metformin, a drug commonly used to treat diabetes, can decrease the amount of COVID-19 virus in the body and lower the chances of the virus coming back strongly after ...

May 2, 2024

0

104

Small molecule shows early-stage promise for repairing myelin sheath damage

When treated with a novel protein function inhibitor called ESI1, mice that mimic the symptoms of multiple sclerosis (MS) and lab-prepared human brain cells both demonstrated the ability to regenerate vital myelin coatings ...

May 2, 2024

0

78

How the brain structure that produces norepinephrine also helps control visual attention

The locus coeruleus (LC) is a small region of the brainstem that produces norepinephrine, a chemical with powerful effects on arousal and wakefulness which plays an important role in the body's response to stress or panic. ...

May 2, 2024

0

51

Study finds young adults reduced drinking during and after pandemic

A new study examined the drinking levels and patterns of young adults before, during and after the pandemic. The researchers found alcohol use and alcohol-related problems substantially decreased in heavy-drinking young adults ...

May 2, 2024

1

50

Testing for residual cancer cells before blood cell transplant therapy is important and practical, new study finds

Patients in remission after battling a high-risk blood cancer are likely to have better outcomes if no trace of the cancer is detectable before the patients receive donor blood cells.

May 2, 2024

0

49

Scientists track 'doubling' in origin of cancer cells

Working with human breast and lung cells, Johns Hopkins Medicine scientists say they have charted a molecular pathway that can lure cells down a hazardous path of duplicating their genome too many times, a hallmark of cancer ...

May 2, 2024

0

42

Four state-of-the-art AI search engines for histopathology images may not be ready for clinical use

Four proposed state-of-the art image search engines for automating search and retrieval of digital histopathology slides were found to be of inadequate performance for routine clinical care, new research suggests.

May 2, 2024

0

40

Friday, May 03

A common type of fiber may trigger bowel inflammation

Inulin, a type of fiber found in certain plant-based foods and fiber supplements, causes inflammation in the gut and exacerbates inflammatory bowel disease in a preclinical model, according to a new study by Weill Cornell ...

May 3, 2024

4

331

People with gas and propane stoves breathe more unhealthy nitrogen dioxide, study finds

A study of air pollution in U.S. homes found that households with gas or propane stoves regularly breathe unhealthy levels of nitrogen dioxide.

May 3, 2024

4

84

Researchers find unexpected link between essential fats and insulin aggregation

Scientists within Texas A&M AgriLife Research have discovered a surprising connection between certain fatty acids and insulin when mixed in solution. Their study, published in ACS Chemical Neuroscience, showed the presence ...

May 3, 2024

0

68

Leprosy drug may be effective in Huntington's disease, study suggests

A preclinical study from Karolinska Institutet offers hope for treating severe neurodegenerative diseases with an existing drug. The study suggests that the leprosy drug clofazimine may be effective in the treatment of Huntington's ...

May 3, 2024

0

67

Researchers discover compounds produced by gut bacteria that can treat inflammation

Researchers at the University of Toronto have found naturally occurring compounds in the gut that can be harnessed to reduce inflammation and other symptoms of digestive issues. This can be achieved by binding the compounds ...

May 3, 2024

0

65

Study reveals how COVID-19 vaccines prevent severe disease

A study by scientists at the University of Oxford, has unveiled crucial insights into the way that COVID-19 vaccines mitigate severe illness in those who have been vaccinated.

May 3, 2024

0

56

Study challenges one-size-fits-all approach to vitamin D supplementation guidelines

A recent study from Trinity College Dublin scientists, sheds light on the complexities of achieving optimal vitamin D status across diverse populations. Despite substantial research on the determinants of vitamin D, levels ...

May 3, 2024

0

53

Saturday, May 04

Healthy teeth are wondrous and priceless: Dentist explains why and how best to protect them

At an auction in England in 2011, one of John Lennon's teeth sold for just over US$31,000.

May 4, 2024

0

48

Major women's health study supports hormone replacement therapy in early menopause

Hormone replacement therapy can safely ease middle-aged women's symptoms during early menopause, data from a major women's health study show.

May 4, 2024

0

35

A world with fewer children? Addressing the despair behind declining fertility

In the 1992 dystopian novel "Children of Men," later adapted to film, humanity faces the chilling reality of a world without children, a global infertility crisis that threatens to extinguish the species. While this apocalyptic ...

May 4, 2024

0

33

New study reveals how teens thrive online: Factors that shape digital success revealed

A new study co-authored by Sophie Janicke-Bowles, associate professor in Chapman University's School of Communication, sheds light on the role that new and traditional media play in promoting and affecting character development, ...

May 4, 2024

0

16

CD7 expression tied to poorer outcomes with newly diagnosed leukemia

CD7 expression is associated with poorer outcomes in patients with newly diagnosed acute myeloid leukemia (AML), according to a study published online April 11 in the British Journal of Haematology.

May 4, 2024

0

7

Research strengthens case to treat COVID-19 with metformin, not ivermectin

Patients with COVID-19 had lower viral loads if treated with metformin, according to new University of Minnesota research that argues for broader use of the cheap anti-diabetes drug and against the controversial use of ivermectin.

May 4, 2024

2

2

Why diversity in nature could be the key to mental well-being

By the time you have finished reading this article, at least one species on our planet will be lost forever.

May 4, 2024

0

2

Sunday, May 05

Can this thumb test tell if you are at increased risk of a hidden aortic aneurysm?

All the parts of our bodies share an inherent connectivity. This goes much further than "the foot bone's connected to the … leg bone." For instance, both hands and feet are connected to a constantly flowing bloodstream, ...

May 5, 2024

0

36

Survey of US parents highlights need for more awareness about newborn screening, cystic fibrosis

A national survey led by Ann & Robert H. Lurie Children's Hospital of Chicago found that parents have insufficient knowledge of newborn screening in general and of cystic fibrosis (CF) in particular. Researchers asked specific ...

May 5, 2024

0

13

Why is cancer called cancer? We need to go back to Greco-Roman times for the answer

One of the earliest descriptions of someone with cancer comes from the fourth century BC. Satyrus, tyrant of the city of Heracleia on the Black Sea, developed a cancer between his groin and scrotum. As the cancer spread, ...

May 5, 2024

0

13

Pickleball injuries and prevention

The popularity of pickleball has exploded in the last few years, and according to a recent report, so have injuries attributed to the relatively new sport.

May 5, 2024

0

1

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