Race to the top: Decoding metastasis
(Medical Xpress) -- One of cancer's greatest and most insidious threats is metastasis – the three-dimensional migratory invasion of cancer cells from primary tumors to a distant part of the body. The ...
Cancer
Apr 29, 2011 |
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Landscape of cancer genes and mutational processes in breast cancer
In a study published today in Nature, researchers describe nine new genes that drive the development of breast cancer. This takes the tally of all genes associated with breast cancer development to 40.
Cancer
7 hours ago |
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One-two punch knocks out aggressive breast cancer cells
Doctors have long known that treating patients with multiple cancer drugs often produces better results than treatment with just a single drug. Now, a study from MIT shows that the order and timing of drug ...
Cancer
May 11, 2012 |
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Researchers use genomics to identify a molecular-based treatment for a viral skin cancer
Four years after they discovered the viral roots of a rare skin cancer, researchers at the University of Pittsburgh Cancer Institute (UPCI) and the School of Medicine have now identified a molecule activated by this virus ...
Cancer
May 09, 2012 |
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Melanoma: Whole-genome sequencing of 25 tumors confirms role of sun damage, reveals new genetic alterations
Melanoma – the deadliest and most aggressive form of skin cancer – has long been linked to time spent in the sun. Now a team led by scientists from the Broad Institute and Dana-Farber Cancer Institute has sequenced ...
Cancer
May 09, 2012 |
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Block its recycling system, and cancer kicks the can: study
All cells have the ability to recycle unwanted or damaged proteins and reuse the building blocks as food. But cancer cells have ramped up the system, called autophagy, and rely on it to escape damage in the face of chemotherapy ...
Cancer
May 08, 2012 |
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Not all tumor cells are equal: Study reveals huge genetic diversity in cells shed by tumors
The cells that slough off from a cancerous tumor into the bloodstream are a genetically diverse bunch, Stanford University School of Medicine researchers have found. Some have genes turned on that give them the potential ...
Cancer
May 07, 2012 |
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Clusters of cooperating tumor-suppressor genes are found in large regions deleted in common cancers
Scientists at Cold Spring Harbor Laboratory (CSHL) and Memorial Sloan-Kettering Cancer Center have amassed strong experimental evidence implying that commonly occurring large chromosomal deletions that are seen in many cancer ...
Cancer
May 07, 2012 |
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New findings contradict current views on cancer stem cells
New findings in breast cancer research by an international team of scientists contradict the prevailing belief that only basal-like cells with stem cell qualities can form invasive tumors. Research led by ...
Cancer
Apr 18, 2012 |
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FLT3 gene mutations play critically important role in acute myeloid leukemia
The key to treating one of the most common types of human leukemia may lie within mutations in a gene called FLT3, according to new research led by physician-scientists at the University of California, San Francisco (UCSF) ...
Cancer
Apr 15, 2012 |
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Two genetic deletions in human genome linked to aggressive prostate cancer development
An international research team led by Weill Cornell Medical College investigators have discovered two inherited-genetic deletions in the human genome linked to development of aggressive prostate cancer. The findings, published ...
Cancer
Apr 09, 2012 |
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Research duo say that far too many preclinical cancer study results are just plain wrong
(Medical Xpress) -- C. Glenn Begley, formerly head of cancer research at pharmaceutical giant Amgen and Lee M. Ellis a cancer researcher at the University of Texas, have published a paper together in Nature that is sure t ...
Cancer
Mar 29, 2012 |
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Imipramine blue: Novel compound halts tumor spread, improves brain cancer treatment in animal studies
Treating invasive brain tumors with a combination of chemotherapy and radiation has improved clinical outcomes, but few patients survive longer than two years after diagnosis. The effectiveness of the treatment ...
Cancer
Mar 28, 2012 |
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The path to personalized cancer treatment
In the largest study of its kind, researchers have profiled genetic changes in cancer with drug sensitivity in order to develop a personalised approach to cancer treatments. The study is published in Nature on Thursday 29 Mar ...
Cancer
Mar 28, 2012 |
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Map of substrate-kinase interactions may lead to more effective cancer drugs
(Medical Xpress) -- Later-stage cancers thrive by finding detours around roadblocks that cancer drugs put in their path, but a Purdue University biochemist is creating maps that will help drugmakers close ...
Cancer
Mar 27, 2012 |
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