Two siblings who have the only known mutations in a key gene anywhere in the world have helped scientists gain new insights that could help progress the search for new treatments in type 1 diabetes.
Apr 18, 2024
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Antibodies produced against the commonly used antibiotic, gentamicin, appear to increase the risk of type 1 diabetes in children already genetically at risk, scientists say.
Dec 8, 2022
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In type 1 diabetes, the body develops immune cells that target pancreatic beta cells, which play a critical role in the production and secretion of insulin. One of the earliest targets of this immune response is a specific ...
Jul 25, 2022
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To an immunologist, autoimmune diseases like Type 1 diabetes are the polar opposite of cancer. In the former, the immune system goes into overdrive and attacks the body's own organs in a relentless manner, eventually causing ...
Nov 30, 2021
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Scientists have completed the largest and most diverse genetic study of Type 1 diabetes ever undertaken, identifying new drug targets to treat a condition that affects 1.3 million American adults.
Jul 22, 2021
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Researchers from the Barbara Davis Center for Childhood Diabetes at the University of Colorado Anschutz Medical Campus have found that immune responses to insulin could help identify individuals most at risk for developing ...
Feb 8, 2021
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It's known that genetics, or an inherited genome, is a major determinant of one's risk for autoimmune diseases, like Type 1 diabetes. In human cells, a person's genome—about six feet of DNA—is compressed into the micrometer ...
Feb 11, 2020
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Autoimmune diseases such as type 1 diabetes are controlled by our genes. While researchers are eager to find out what other factors could contribute to this disease, a new study published by Yale researchers provides direct ...
Sep 12, 2017
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Doctors can't predict who will develop type 1 diabetes, a chronic autoimmune disease in which the immune system destroys the cells needed to control blood-sugar levels, requiring daily insulin injections and continual monitoring.
Jul 11, 2017
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Early in embryological development, the immune system learns not to attack the body's own cells. In many autoimmune diseases, including type 1 diabetes, multiple sclerosis, and rheumatoid arthritis, this self-tolerance is ...
Apr 12, 2017
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