Childhood Cancer

Study finds mutations linked to relapse of childhood leukemia

After an intensive three-year hunt through the genome, medical researchers have pinpointed mutations that leads to drug resistance and relapse in the most common type of childhood cancer—the first time anyone has linked ...

Genetics created Feb 03, 2013 | popularity not rated yet | comments 0 | with audio podcast

Tumors evolve rapidly in a childhood cancer, leaving fewer obvious tumor targets

An extensive genomic study of the childhood cancer neuroblastoma reinforces the challenges in treating the most aggressive forms of this disease. Contrary to expectations, the scientists found relatively few recurrent gene ...

Genetics created Jan 20, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

New gene variants raise risk of neuroblastoma, influence tumor progression

Researchers have discovered two gene variants that raise the risk of the pediatric cancer neuroblastoma. Using automated technology to perform genome-wide association studies on DNA from thousands of subjects, the study broadens ...

Genetics created Sep 04, 2012 | popularity not rated yet | comments 0 | with audio podcast

Cancer sequencing project identifies potential approaches to combat aggressive leukemia

Researchers have discovered that a subtype of leukemia characterized by a poor prognosis is fueled by mutations in pathways distinctly different from a seemingly similar leukemia associated with a much better outcome. The ...

Cancer created Jan 11, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Key to fighting drug-resistant leukemia found

Doctors who treat children with the most common form of childhood cancer – acute lymphoblastic leukemia – are often baffled at how sometimes the cancer cells survive their best efforts and the most powerful modern ...

Cancer created May 18, 2011 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Common anti-inflammatory coaxes liver cancer cells to commit suicide

The anti-inflammatory drug celecoxib, known by the brand name Celebrex, triggers liver cancer cell death by reacting with a protein in a way that makes those cells commit suicide, according to a new study.

Cancer created May 16, 2011 | popularity 4.3 / 5 (6) | comments 0 | with audio podcast

Study finds potential link between auto pollution, some childhood cancers

Scientists from UCLA's Fielding School of Public Health led by Julia Heck, an assistant researcher in the school's epidemiology department and a member of UCLA's Jonsson Comprehensive Cancer Center, have found a possible ...

Cancer created Apr 09, 2013 | popularity not rated yet | comments 0 | with audio podcast

New genetic link found between normal fetal growth and cancer

Two researchers at the National Institutes of Health discovered a new genetic link between the rapid growth of healthy fetuses and the uncontrolled cell division in cancer. The findings shed light on normal development and ...

Genetics created Apr 09, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

T-cell therapy eradicates an aggressive leukemia in two children

Two children with an aggressive form of childhood leukemia had a complete remission of their disease-showing no evidence of cancer cells in their bodies-after treatment with a novel cell therapy that reprogrammed their immune ...

Cancer created Mar 25, 2013 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Inherited genetic variations have a major impact on childhood leukemia risk

Humans have between 20,000 and 25,000 genes that carry instructions for assembling the proteins that do the work of cells. Work led by St. Jude Children's Research Hospital found that children who inherit certain variations ...

Cancer created Mar 19, 2013 | popularity not rated yet | comments 0 | with audio podcast

Vital children's cancer drug being underdosed

(Medical Xpress)—A study has found that many patients receiving a potentially life-saving drug for the childhood cancer neuroblastoma are potentially being under-dosed. Every year in the UK approximately 100 children aged ...

Cancer created Jan 18, 2013 | popularity not rated yet | comments 0

Drug shortage linked to greater risk of relapse in young Hodgkin lymphoma patients

A national drug shortage has been linked to a higher rate of relapse among children, teenagers and young adults with Hodgkin lymphoma enrolled in a national clinical trial, according to research led by St. Jude Children's ...

Cancer created Dec 26, 2012 | popularity not rated yet | comments 0 | with audio podcast

Gene sequencing project identifies abnormal gene that launches rare childhood leukemia

Research led by the St. Jude Children's Research Hospital – Washington University Pediatric Cancer Genome Project has identified a fusion gene responsible for almost 30 percent of a rare subtype of childhood leukemia with ...

Cancer created Nov 12, 2012 | popularity not rated yet | comments 0 | with audio podcast

Study suggests stem cell transplant survivors at increased risk of developing heart disease

New research appearing online today in Blood, the journal of the American Society of Hematology (ASH), suggests that long-term survivors of hematopoietic cell transplants (HCT) are at an increased risk of developing hear ...

Cardiology created Oct 03, 2012 | popularity not rated yet | comments 0 | with audio podcast

Whole-genome scan helps select best treatment for childhood cancer

A whole-genome scan to identify large-scale chromosomal damage can help doctors choose the best treatment option for children with neuroblastoma, one of the most common types of childhood cancer, finds an international collaboration ...

Cancer created Sep 14, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast


The Childhood Cancer Research Group' (CCRG) is part of the University Department of Paediatrics at the University of Oxford, England. The CCRG maintains the National Registry of Childhood Tumours (NRCT), which is said to be the largest childhood cancer registry in the world.

This text uses material from Wikipedia and is available under the GNU Free Documentation License.

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