Childhood Cancer
Study finds mutations linked to relapse of childhood leukemia
After an intensive three-year hunt through the genome, medical researchers have pinpointed mutations that leads to drug resistance and relapse in the most common type of childhood cancer—the first time anyone has linked ...
Genetics
Feb 03, 2013 |
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Tumors evolve rapidly in a childhood cancer, leaving fewer obvious tumor targets
An extensive genomic study of the childhood cancer neuroblastoma reinforces the challenges in treating the most aggressive forms of this disease. Contrary to expectations, the scientists found relatively few recurrent gene ...
Genetics
Jan 20, 2013 |
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New gene variants raise risk of neuroblastoma, influence tumor progression
Researchers have discovered two gene variants that raise the risk of the pediatric cancer neuroblastoma. Using automated technology to perform genome-wide association studies on DNA from thousands of subjects, the study broadens ...
Genetics
Sep 04, 2012 |
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Cancer sequencing project identifies potential approaches to combat aggressive leukemia
Researchers have discovered that a subtype of leukemia characterized by a poor prognosis is fueled by mutations in pathways distinctly different from a seemingly similar leukemia associated with a much better outcome. The ...
Cancer
Jan 11, 2012 |
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Key to fighting drug-resistant leukemia found
Doctors who treat children with the most common form of childhood cancer acute lymphoblastic leukemia are often baffled at how sometimes the cancer cells survive their best efforts and the most powerful modern ...
Cancer
May 18, 2011 |
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Common anti-inflammatory coaxes liver cancer cells to commit suicide
The anti-inflammatory drug celecoxib, known by the brand name Celebrex, triggers liver cancer cell death by reacting with a protein in a way that makes those cells commit suicide, according to a new study.
Cancer
May 16, 2011 |
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Study finds potential link between auto pollution, some childhood cancers
Scientists from UCLA's Fielding School of Public Health led by Julia Heck, an assistant researcher in the school's epidemiology department and a member of UCLA's Jonsson Comprehensive Cancer Center, have found a possible ...
Cancer
Apr 09, 2013 |
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New genetic link found between normal fetal growth and cancer
Two researchers at the National Institutes of Health discovered a new genetic link between the rapid growth of healthy fetuses and the uncontrolled cell division in cancer. The findings shed light on normal development and ...
Genetics
Apr 09, 2013 |
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T-cell therapy eradicates an aggressive leukemia in two children
Two children with an aggressive form of childhood leukemia had a complete remission of their disease-showing no evidence of cancer cells in their bodies-after treatment with a novel cell therapy that reprogrammed their immune ...
Cancer
Mar 25, 2013 |
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Inherited genetic variations have a major impact on childhood leukemia risk
Humans have between 20,000 and 25,000 genes that carry instructions for assembling the proteins that do the work of cells. Work led by St. Jude Children's Research Hospital found that children who inherit certain variations ...
Cancer
Mar 19, 2013 |
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Vital children's cancer drug being underdosed
(Medical Xpress)—A study has found that many patients receiving a potentially life-saving drug for the childhood cancer neuroblastoma are potentially being under-dosed. Every year in the UK approximately 100 children aged ...
Cancer
Jan 18, 2013 |
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Drug shortage linked to greater risk of relapse in young Hodgkin lymphoma patients
A national drug shortage has been linked to a higher rate of relapse among children, teenagers and young adults with Hodgkin lymphoma enrolled in a national clinical trial, according to research led by St. Jude Children's ...
Cancer
Dec 26, 2012 |
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Gene sequencing project identifies abnormal gene that launches rare childhood leukemia
Research led by the St. Jude Children's Research Hospital – Washington University Pediatric Cancer Genome Project has identified a fusion gene responsible for almost 30 percent of a rare subtype of childhood leukemia with ...
Cancer
Nov 12, 2012 |
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Study suggests stem cell transplant survivors at increased risk of developing heart disease
New research appearing online today in Blood, the journal of the American Society of Hematology (ASH), suggests that long-term survivors of hematopoietic cell transplants (HCT) are at an increased risk of developing hear ...
Cardiology
Oct 03, 2012 |
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Whole-genome scan helps select best treatment for childhood cancer
A whole-genome scan to identify large-scale chromosomal damage can help doctors choose the best treatment option for children with neuroblastoma, one of the most common types of childhood cancer, finds an international collaboration ...
Cancer
Sep 14, 2012 |
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The Childhood Cancer Research Group' (CCRG) is part of the University Department of Paediatrics at the University of Oxford, England. The CCRG maintains the National Registry of Childhood Tumours (NRCT), which is said to be the largest childhood cancer registry in the world.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
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