Cystic fibrosis is one of the most common inherited single gene diseases, with an incidence of 1 out of 3,000 newborns in central Europe. An EU study developed a novel gene therapy approach for improving fluid absorption ...
Sep 20, 2012
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The lung clearance index (LCI) is a sensitive non-invasive marker of early lung disease in young children with cystic fibrosis (CF), according to a new study from Australian researchers.
Jan 27, 2012
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Meara Schmidt, 28, almost died a few weeks ago. Lying in her hospital bed at UCLA, the seriously ill cystic fibrosis patient felt herself slipping away and her life flashing by. But then the image of her husband appeared, ...
Jul 6, 2012
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In recent decades, treatment options for people with cystic fibrosis have improved dramatically. The newest drugs, known as potentiators, target a protein called cystic fibrosis transmembrane conductance regulator, which ...
Jul 9, 2019
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For many inherited diseases, such as cystic fibrosis or Huntington disease, the disease-causing genetic mutation damages or removes a protein that has an essential role in the body. This protein defect is the root cause of ...
Aug 8, 2013
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The lower airways of patients with cystic fibrosis (CF) have unique biochemical features that correlate with the complex communities of lung bacteria typical of this disease, according to a multicenter study led by researchers ...
Mar 23, 2022
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Building upon work initiated by University of Alabama scientists, Harvard Medical School researchers, collaborating with UA and others, took another step in cracking the code behind a protein’s precise role in the ...
Jul 13, 2011
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Researchers have identified a rare cell type in airway tissue, previously uncharacterized in the scientific literature, that appears to play a key role in the biology of cystic fibrosis. Using new technologies that enable ...
Aug 1, 2018
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People with cystic fibrosis (CF) suffer repeated lung infections because their airway mucus is too thick and sticky to keep bacteria, viruses, and other pathogens from causing chronic infection. How mucus becomes abnormal ...
Mar 23, 2017
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Mucus is important for maintaining healthy lungs. Inhaled particles, including bacteria and viruses, get trapped in mucus and then cilia—tiny hair like projections on the surface of the airway cells—sweep the mucus out ...
Jun 28, 2017
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