After an intensive three-year hunt through the genome, medical researchers have pinpointed mutations that leads to drug resistance and relapse in the most common type of childhood cancer—the first time anyone has linked ...
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B cells can generate different 'classes' of antibodies, each of which carries a specific type of protein chain that triggers a specific downstream cascade of immune responses. Immunoglobulin M (IgM) antibodies, ...
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Biologists at Tufts University School of Arts and Sciences have discovered a bioelectric signal that can identify cells that are likely to develop into tumors. The researchers also found that they could lower ...
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If the focus on cancer sometimes tilts toward its impact in rich, industrialized nations, statistics show that the disease is a scourge all around the world, with 95 percent of cancer deaths occurring in ...
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(HealthDay)—The anti-cancer drug Gleevec (imatinib) has received new U.S. Food and Drug Administration approval to treat the most common type of pediatric cancer, affecting some 2,900 children each year, the agency said ...
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Boca Raton, Fla., parents Gary and Judy Susser say they know the hope and promise of stem-cell therapy. Nine years ago they traveled to Mexico for stem cell injections for their son Adam, who has cerebral palsy.
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Genome sequencing data once regarded as junk is now being used to gain important clues to help understand disease. The latest example comes from the St. Jude Children's Research Hospital – Washington University Pediatric ...
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A clinical trial to evaluate a drug candidate called cyclodextrin as a possible treatment for Niemann-Pick disease type C1 (NPC), a rare and fatal genetic disease, will start today, researchers announced. Scientists from ...
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Researchers at Imperial College London have shown that keeping healthy blood cells alive could be a more important tool in the fight against leukaemia than keeping cancerous cells at bay.
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Research led by St. Jude Children's Research Hospital scientists has identified a possible lead in treatment of two childhood leukemia subtypes known for their dramatic loss of chromosomes and poor treatment outcomes.
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University of Rochester Medical Center scientists have proposed a new reason why acute myeloid leukemia, one of the most aggressive cancers, is so difficult to cure: a subset of cells that drive the disease appear to have ...
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Researchers at the University of California, San Diego School of Medicine have discovered that hard-to-reach, drug-resistant leukemia stem cells (LSCs) that overexpress multiple pro-survival protein forms ...
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(HealthDay)—For patients treated for Hodgkin's lymphoma (HL), cumulative doses of alkylating agent (AA) is associated with the risk of therapy-related acute myeloid leukemia/myelodysplastic syndrome (t-AML/MDS), ...
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Data published online today in Blood, the Journal of the American Society of Hematology (ASH) describe the work of an ASH international clinical network collaborative focused on modernizing treatment protocols for patien ...
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(Medical Xpress)—An international team of researchers has developed a new anti-cancer drug that holds promise as a therapy that fights cancer while causing fewer side effects than current medicines. The ...
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A shot in the arm for old antibiotics: Silver boosts antibiotics
Slipping bacteria some silver could give old antibiotics new life, scientists at the Wyss Institute for Biologically Inspired Engineering at Harvard University reported June 19 in Science Translational Me ...
Validating maps of the brain's resting state
Kick back and shut your eyes. Now stop thinking. You have just put your brain into what neuroscientists call its resting state. What the brain is doing when an individual is not focused on the outside world ...
Scientists create way to see structures that store memories in living brain
Oscar Wilde called memory "the diary that we all carry about with us." Now a team of scientists has developed a way to see where and how that diary is written.
Wireless subretinal prostheses allows blind mice to see light
(Medical Xpress)—A team of researchers from the U.S. and Scotland has developed a new type of retinal prostheses designed to restore sight to blind patients. In their paper published in the journal Nature Co ...
Diapocynin, a synthetic molecule derived from a naturally occurring compound (apocynin), has been found to protect neurobehavioral function in mice with Parkinson's Disease symptoms by preventing deficits in motor coordination.
Distracted walking: Injuries soar for pedestrians on phones
More than 1,500 pedestrians were estimated to be treated in emergency rooms in 2010 for injuries related to using a cell phone while walking, according to a new nationwide study.
Researchers pinpoint how smoking causes osteoporosis
(Medical Xpress)—Human bone breaks down and regenerates naturally all the time, in a perfectly balanced dance that maintains skeletal integrity.
Laughing gas does not increase heart attacks
(Medical Xpress)—Nitrous oxide—best known as laughing gas—is one of the world's oldest and most widely used anesthetics. Despite its popularity, however, experts have questioned its impact on the risk ...
Model recreates wear and tear of osteoarthritis
(Medical Xpress)—There's a reason osteoarthritis is often called wear-and-tear arthritis: Repeated stress on joints over time results in degeneration of the soft cartilage that normally distributes loads ...
Study of vocal impersonations reveals how we manipulate our voices
A study of vocal impersonations has shown for the first time how speech production and voice perception systems in the brain interact to influence the way our voices sound. The research, supported by the ...
