More-effective therapies are greatly needed for children with the high-risk blood cancer T-cell acute lymphoblastic leukemia (T-ALL). St. Jude Children's Research Hospital scientists have leveraged the latest chemical technology ...
Aug 24, 2022
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Babies with leukemia could get an array of new treatments after scientists used genetic engineering to reproduce a gene defect found in the disease.
Oct 7, 2022
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UConn associate professor of pharmaceutics Xiuling Lu, along with professor of chemistry Rajeswari M. Kasi, was part of a team that recently published a paper in Nature Cell Biology finding a commonly used chemotherapy drug ...
Jun 18, 2020
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Acute myeloid leukemia is a conundrum among cancers. Immature cells swamp the bone marrow, crowd out healthy cells, and all too often can have devastating consequences.
Apr 24, 2015
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Patients who potentially could benefit most from participation in clinical trials due to poor prognoses often are not included based on eligibility criteria, such as existing medical illnesses. A novel study at The University ...
Dec 3, 2016
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Testing for DNMT3A mutations in FLT3-ITD subgroup of AML patients at the point of diagnosis and post-chemotherapy could improve treatment and predict chances of relapse and survival rates respectively
Jul 11, 2016
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Patients participating in The Leukemia & Lymphoma Society's (LLS) groundbreaking precision medicine Beat AML Master Clinical Trial had superior outcomes compared to acute myeloid leukemia (AML) patients who opted for standard ...
Oct 27, 2020
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A new study by researchers at the RIKEN Center for Integrative Medical Science in Japan reports differences in blood cell mutations between Japanese and European populations. The study found that these pre-clinical mutations ...
Jun 24, 2020
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A new targeted drug, studied by researchers at The Ohio State University Comprehensive Cancer Center—Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC—James), may offer a new treatment option ...
Nov 6, 2023
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Chronic lymphocytic leukemia (CLL) is one of the most common blood cancers in adults. The disease originates in B cells—the part of the immune system that produces antibodies—and then evolves slowly, typically affecting ...
Apr 21, 2022
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