Liver Transplant
Large-scale genetic study defines relationship between primary sclerosing cholangitis and other autoimmune diseases
For the first time, scientists show that a leading cause of liver transplant, primary sclerosing cholangitis (PSC), is a distinct disease from inflammatory bowel disease, opening up new avenues for specific PSC treatments.
Genetics
Apr 21, 2013 |
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Study reveals how the world's first drug for amyloid disease works
Scientists from The Scripps Research Institute and Pfizer Inc. have published a new study showing how a new drug called tafamidis (Vyndaqel) works. Tafamidis, approved for use in Europe and currently under ...
Medical research
May 29, 2012 |
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Entry point for hepatitis C infection identified
A molecule embedded in the membrane of human liver cells that aids in cholesterol absorption also allows the entry of hepatitis C virus, the first step in hepatitis C infection, according to research at the University of ...
Diseases, Conditions, Syndromes
Jan 24, 2012 |
4.5 / 5 (2) |
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First trial of a new hepatitis C vaccine shows promise
(Medical Xpress) -- A new vaccine against the chronic liver disease hepatitis C has shown promising results in a first clinical trial in humans, Oxford University researchers report.
Diseases, Conditions, Syndromes
Jan 05, 2012 |
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New gene therapy methods accurately correct mutation in patient's stem cells
For the first time, scientists have cleanly corrected a human gene mutation in a patient's stem cells. The result, reported in Nature on Wednesday 12 October, brings the possibility of patient-specific therapies closer to bec ...
Genetics
Oct 12, 2011 |
4.6 / 5 (10) |
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Adult stem cells take root in livers and repair damage
Johns Hopkins researchers have demonstrated that human liver cells derived from adult cells coaxed into an embryonic state can engraft and begin regenerating liver tissue in mice with chronic liver damage.
Medical research
May 11, 2011 |
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Sunshine hormone, vitamin D, may offer hope for treating liver fibrosis
Liver fibrosis results from an excessive accumulation of tough, fibrous scar tissue and occurs in most types of chronic liver diseases. In industrialized countries, the main causes of liver injury leading ...
Medical research
Apr 25, 2013 |
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Computer modeling reveals how surprisingly potent hepatitis C drug works
A study by researchers from Los Alamos National Laboratory and a multinational team reveals how daclatasvir, a direct-acting antiviral agent in development for the treatment of hepatitis C virus (HCV), targets one of its ...
Diseases, Conditions, Syndromes
Feb 18, 2013 |
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Paired CT scans catch chemo-killing of liver tumors in real time
Using two successive pairs of specialized CT scans, a team of Johns Hopkins and Dutch radiologists has produced real-time images of liver tumors dying from direct injection of anticancer drugs into the tumors and their surrounding ...
Cancer
Jan 01, 2013 |
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Sustained virological response linked with improved survival for patients with chronic HCV infection
Among patients with chronic hepatitis C virus infection and advanced hepatic fibrosis (development of excess fibrous connective tissue), sustained virological response (SVR) to interferon-based treatment was associated with ...
Diseases, Conditions, Syndromes
Dec 25, 2012 |
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Researchers discover how hepatitis C virus reprograms human liver cells
Hepatitis C virus has evolved to invade and hijack the basic machinery of the human liver cell to ensure its survival and spread. Researchers at the University of North have discovered how hepatitis C binds ...
Diseases, Conditions, Syndromes
Dec 18, 2012 |
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Researchers find clue to how Hepatitis C virus harms liver
Researchers at the University of Southern California (USC) have discovered a trigger by which the Hepatitis C virus enters liver cells ─ shedding light on how this serious and potentially deadly virus can begin to damage ...
Diseases, Conditions, Syndromes
Dec 12, 2012 |
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Mice with 'humanized' livers improve early drug testing
Stanford University School of Medicine scientists have used bioengineered mice with livers composed largely of human cells to characterize a drug about to enter early-stage clinical development for combating hepatitis C.
Medical research
Oct 31, 2012 |
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Abbott Labs rises on hepatitis C drug data (Update)
Abbott Laboratories said Monday that its experimental hepatitis C drug regimen cured 99 percent of patients in a midstage study with the most common and hardest-to-treat type of the disease.
Medications
Oct 15, 2012 |
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Single-port kidney removal through the belly button boosts living-donor satisfaction
In the largest study of its kind, living donors who had a kidney removed through a single port in the navel report higher satisfaction in several key categories, compared to donors who underwent traditional multiple-port ...
Surgery
Sep 12, 2012 |
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Liver transplantation or hepatic transplantation is the replacement of a diseased liver with a healthy liver allograft. The most commonly used technique is orthotopic transplantation, in which the native liver is removed and replaced by the donor organ in the same anatomic location as the original liver. Liver transplantation nowadays is a well accepted treatment option for end-stage liver disease and acute liver failure. Typically three surgeons and one anesthesiologist are involved, with up to four supporting nurses. The surgical procedure is very demanding and ranges from 4 to 18 hours depending on outcome. Numerous anastomoses and sutures, and many disconnections and reconnections of abdominal and hepatic tissue, must be made for the transplant to succeed, requiring an eligible recipient and a well-calibrated live or cadaveric donor match. By any standard, hepatic transplantation is a major surgical procedure with an appreciable degree of risk.[citation needed]
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
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