A new nuclear medicine method for detecting malignant melanoma, one of the most aggressive skin cancers, has been successfully tested for the first time in humans and could improve detection of both primary and metastatic ...
Jan 17, 2019
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When melanoma turns metastatic, it spreads to the brain in more than 40% of patients. A study by Yale Cancer Center researchers published today in the Journal of Clinical Oncology (JCO) shows a checkpoint inhibitor immunotherapy ...
Nov 9, 2018
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A UCLA-led study has found that a treatment that uses a bacteria-like agent in combination with an immunotherapy drug could help some people with advanced melanoma, an aggressive form of skin cancer, live longer.
Aug 28, 2018
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Cancer cells are more than a lump of cells growing out of control; they participate in active combat with the immune system for their own survival. Being able to evade the immune system is a hallmark of cancer. Cancer cells ...
Aug 8, 2018
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UC San Francisco researchers have identified the sequence of genetic changes that transform benign moles into malignant melanoma in a large cohort of human skin cancer patients and have used CRISPR gene editing to recreate ...
Jul 9, 2018
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Most cells in the human body have a cilium, a slender cell protuberance that picks up signals from the cell's external environment. Researchers at the University of Zurich have now shown that these fine sensory antennae play ...
Jul 2, 2018
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University of Otago research provides insights into an underlying mechanism that could explain why new cancer therapies to help treat metastatic melanoma do not always work on patients, paving the way for predicting which ...
Jun 29, 2018
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Patients with advanced or metastatic melanoma have been able to live longer cancer-free lives because of several new therapies approved over the last decade, such as BRAF and MEK inhibitors. However, despite the success of ...
Apr 19, 2018
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A combination of CMP-001, an intratumoral Toll-like receptor 9 (TLR9) agonist, and pembrolizumab (Keytruda), tested in patients with metastatic melanoma resistant to PD-1 checkpoint inhibition, was well tolerated and had ...
Apr 17, 2018
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Obese patients with metastatic melanoma live significantly longer than those with normal body mass indexes (BMI), according to a new study published in Lancet Oncology. The surprising association was mainly seen in male patients ...
Mar 26, 2018
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