Squamous Cell Carcinoma

Risk factors ID'd for poor cutaneous cell CA outcomes

(HealthDay)—The risks of metastasis and death associated with cutaneous squamous cell carcinoma (CSCC) are low, but significant, and risk factors for poor outcome include tumor diameter, invasion beyond ...

Cancer created 14 hours ago | popularity not rated yet | comments 0 | with audio podcast

Researchers discover possible trigger for spread of head and neck cancer cells

(Medical Xpress)—Very little has been known about the epigenetic events—developmental and environmental factors affecting genes—that occur prior to the invasive growth of head and neck squamous cell carcinomas and their ...

Cancer created May 08, 2013 | popularity not rated yet | comments 0

Reseach reveals genomic similarities between breast cancer, ovarian cancers

One subtype of breast cancer shares many genetic features with high-grade serous ovarian cancer, a cancer that is very difficult to treat, according to researchers supported by the National Institutes of ...

Cancer created Sep 23, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Grape seed extract kills head and neck cancer cells, leaves healthy cells unharmed

Nearly 12,000 people will die of head and neck cancer in the United States this year and worldwide cases will exceed half a million.

Cancer created Jan 27, 2012 | popularity 4.8 / 5 (55) | comments 18 | with audio podcast

Surgery for nonfatal skin cancers might not be best for elderly patients

Surgery is often recommended for skin cancers, but older, sicker patients can endure complications as a result and may not live long enough to benefit from the treatment.

Cancer created Apr 29, 2013 | popularity not rated yet | comments 1

Immortality gene mutation identifies brain tumors, other cancers

Newly identified mutations in a gene that makes cells immortal appear to play a pivotal role in three of the most common types of brain tumors, as well as cancers of the liver, tongue and urinary tract, according to research ...

Cancer created Mar 18, 2013 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Definition of lung squamous cell carcinoma genome opens doors to better, more targeted therapies

A new paper published online in Nature holds out hope that people with the second most common type of lung cancer may one day benefit from targeted therapies that have transformed treatments for other lung cancer patients.

Cancer created Sep 09, 2012 | popularity not rated yet | comments 0 | with audio podcast

Combination of targeted treatment drugs delays resistance in melanoma patients

Combined treatment with two drugs targeting different points in the same growth-factor pathway delayed the development of treatment resistance in patients with BRAF-positive metastatic malignant melanoma. The results of a ...

Cancer created Sep 29, 2012 | popularity not rated yet | comments 0

Common food preservative may slow, even stop tumor growth

Nisin, a common food preservative, may slow or stop squamous cell head and neck cancers, a University of Michigan study found.

Cancer created Oct 31, 2012 | popularity 4.8 / 5 (6) | comments 0 | with audio podcast

Study uncovers mechanism by which melanoma drug accelerates secondary skin cancers

Patients with metastatic melanoma taking the recently approved drug vemurafenib (Zelboraf) responded well to the twice daily pill, but some of them developed a different, secondary skin cancer. Now, researchers at UCLA's ...

Cancer created Jan 18, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Study pinpoints epigenetic function of common cancer-causing protein—it's not what science thought

(Medical Xpress)—Squamous cell carcinoma (SCC) is diagnosed in about 700,000 people in the United States every year. Commonly contributing to SCC is a protein called DNp63a – it goes abnormally high and the ability of ...

Genetics created Sep 26, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

New study links tanning beds to non-melanoma skin cancer

Indoor tanning beds can cause non-melanoma skin cancer – and the risk is greater the earlier one starts tanning, according to a new analysis led by UCSF.

Cancer created Oct 02, 2012 | popularity 5 / 5 (2) | comments 1 | with audio podcast

Researchers observe an increased risk of cancer in people with history of non-melanoma skin cancer

A prospective study by researchers at Brigham and Women's Hospital (BWH) observed an association between risk of second primary cancer and history of non-melanoma skin cancer in white men and women.

Cancer created Apr 23, 2013 | popularity not rated yet | comments 0

Drugs are first to topically deliver gene therapy via commercial moisturizers for skin disease treatment

"Getting under your skin" takes on a brave new meaning thanks to Northwestern University research that could transform gene regulation.

Medical research created Jul 02, 2012 | popularity 5 / 5 (1) | comments 1 | with audio podcast

Early childhood neglect may raise risk of adult skin cancer

Skin cancer patients whose childhood included periods of neglect or maltreatment are at a much greater risk for their cancers to return when they face a major stressful event, based on a new study.

Psychology & Psychiatry created Jun 04, 2012 | popularity 4 / 5 (4) | comments 0 | with audio podcast


Squamous cell carcinoma (SCC or SqCC) is a form of skin cancer. Skin cancers fall into two groups, melanoma and non-melanoma; squamous cell carcinoma is a non-melanoma cancer. It is one of the most common cancers in humans and other animals.

Squamous cells are a type of epithelium cell forming the outermost layers of the skin and some organs in the body. Squamous cell carcinoma usually occurs on the skin, especially portions commonly exposed to the Sun, the face, ears, neck, hands, or arm. The main symptom is a growing bump that may have a rough, scaly surface and flat reddish patches. It may also occur inside the body wherever squamous cells are found, including the esophagus, urinary bladder, prostate, lung, vagina, and cervix, among others.

Despite the common name, squamous cell carcinomas arising in different body sites can show tremendous differences in their presenting signs and symptoms, natural history, prognosis, and response to treatment.

Though the use of these terms has been decreasing in the literature, SqCC is still sometimes referred to as "epidermoid carcinoma" and "squamous cell epithelium". During its earliest stages, it is sometimes known as "Bowen's disease".

This text uses material from Wikipedia and is available under the GNU Free Documentation License.

Latest Spotlight News

AIDS science at 30: 'Cure' now part of lexicon

Big names in medicine are set to give an upbeat assessment of the war on AIDS on Tuesday, 30 years after French researchers identified the virus that causes the disease.

For combat veterans suffering from post-traumatic stress disorder, 'fear circuitry' in the brain never rests

Chronic trauma can inflict lasting damage to brain regions associated with fear and anxiety. Previous imaging studies of people with post-traumatic stress disorder, or PTSD, have shown that these brain regions can over-or ...

Temporal processing in the olfactory system

The neural machinery underlying our olfactory sense continues to be an enigma for neuroscience. A recent review in Neuron seeks to expand traditional ideas about how neurons in the olfactory bulb might encode information about ...

Melon focus headband turns to Kickstarter for rollout plans

(Medical Xpress)—What if the quality of your work depends more on your focus on the piano keys or canvas or laptop than your musical or painting or computing skills? If target users can be convinced, they ...

Now we know why old scizophrenia medicine works on antibiotics-resistant bacteria

In 2008 researchers from the University of Southern Denmark showed that the drug thioridazine, which has previously been used to treat schizophrenia, is also a powerful weapon against antibiotic-resistant bacteria such as ...

Study identifies new approach to improving treatment for MS and other conditions

(Medical Xpress)—Working with lab mice models of multiple sclerosis (MS), UC Davis scientists have detected a novel molecular target for the design of drugs that could be safer and more effective than current FDA-approved ...

College women exceed NIAAA drinking guidelines more frequently than college men

In order to avoid harms associated with alcohol consumption, in 2009 the National Institute on Alcohol Abuse and Alcoholism issued guidelines that define low-risk drinking. These guidelines differ for men and women: no more ...

Individuals who drink heavily and smoke may show 'early aging' of the brain

Treatment for alcohol use disorders works best if the patient actively understands and incorporates the interventions provided in the clinic. Multiple factors can influence both the type and degree of neurocognitive abnormalities ...

Little evidence for prediction rules for low back pain

(HealthDay)—Few randomized clinical trials have been done to assess clinical prediction rules for patients with lower back pain, and the trials that have been done are of low quality and do not provide ...

Skydiving is never plane sailing

Skydivers show the same level of physical stress before every jump whether a first-timer or experienced jumper, say Northumbria researchers.