Some genes are known to drive cancer, and astonishing new research shows why: Mutations in the noncoding regions become functional, altering the abundance of messenger RNA, or mRNA, and potentially facilitating cell proliferation. ...
Apr 18, 2024
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Common inherited genetic factors that predict cancer risk in the general population may also predict elevated risk of new cancers among childhood cancer survivors, according to a study led by researchers at the National Cancer ...
Mar 7, 2024
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Researchers at the University of Colorado Anschutz Medical Campus studying interactions between nerves and tumor microenvironments have found that commonly used drugs like botox may stop or slow the progression of certain ...
Feb 28, 2024
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Scientists from Queen Mary University of London have discovered two new genes that cause head and neck cancer patients to be resistant to chemotherapy, and that silencing either gene can make cancer cells previously unresponsive ...
Sep 4, 2023
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Equipping cancer-infecting (oncolytic) viruses with tumor-inhibiting genetic cargo stimulates the immune system and helps immunotherapy to shrink or completely clear aggressive tumors in mice, according to a new study in ...
Aug 14, 2023
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A new study has shown how, on average, people in the UK have facial skin that is far more DNA damaged from the sun than people in Singapore, explaining the far higher risk of developing the most common skin cancers in the ...
Aug 3, 2023
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Cases of human papillomavirus (HPV)-associated cancers of the head and neck, known as head and neck squamous cell carcinoma (HNSCC), are rapidly increasing throughout the United States. Unfortunately, relatively little is ...
Jul 31, 2023
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For patients with some types of cancer, diagnosis can happen at an advanced stage. While a tumor grows unnoticed, it accumulates hundreds to thousands of mutations, making it difficult for scientists studying late-stage cancers ...
Apr 21, 2023
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Researchers at University of California San Diego School of Medicine and Moores Cancer Center at UC San Diego Health have identified a strong association between the product of a gene expressed in most cancers, including ...
Mar 13, 2023
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A one-year, placebo-controlled trial of oral nicotinamide (vitamin B3) therapy by the University of Sydney did not lead to lower rates of skin cancer in organ transplant recipients. The result is in striking contrast to a ...
Squamous cell carcinoma (SCC or SqCC) is a form of skin cancer. Skin cancers fall into two groups, melanoma and non-melanoma; squamous cell carcinoma is a non-melanoma cancer. It is one of the most common cancers in humans and other animals.
Squamous cells are a type of epithelium cell forming the outermost layers of the skin and some organs in the body. Squamous cell carcinoma usually occurs on the skin, especially portions commonly exposed to the Sun, the face, ears, neck, hands, or arm. The main symptom is a growing bump that may have a rough, scaly surface and flat reddish patches. It may also occur inside the body wherever squamous cells are found, including the esophagus, urinary bladder, prostate, lung, vagina, and cervix, among others.
Despite the common name, squamous cell carcinomas arising in different body sites can show tremendous differences in their presenting signs and symptoms, natural history, prognosis, and response to treatment.
Though the use of these terms has been decreasing in the literature, SqCC is still sometimes referred to as "epidermoid carcinoma" and "squamous cell epithelium". During its earliest stages, it is sometimes known as "Bowen's disease".
This text uses material from Wikipedia licensed under CC BY-SA
