Much of the human genome is made of regulatory regions that control which genes are expressed at a given time within a cell. Those regulatory elements can be located near a target gene or up to 2 million base pairs away from ...
May 8, 2023
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Doug Millay, Ph.D., a scientist with the Division of Molecular Cardiovascular Biology at Cincinnati Children's has dedicated his career to revealing the most fundamental mechanisms of skeletal muscle development. He has been ...
Apr 28, 2023
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Using a new approach for studying live embryonic mouse brains at single-cell resolution, researchers have identified an active multi-layer circuit that forms in the cortex during an unexpectedly early stage of development. ...
Apr 17, 2023
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Testing the efficacy of a vaccine candidate is typically a long process, with the immune response of an animal model taking around two months.
Apr 12, 2023
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In mice with melanoma, probiotic bacteria travel from the gut and establish in tumors, where they directly stimulate immune cells to make cancer immunotherapy more effective, according to a new study led by University of ...
Apr 6, 2023
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Aging (senescent) cells, which stop dividing but don't die, can accumulate in the body over the years and fuel chronic inflammation that contributes to conditions such as cancer and degenerative disorders.
Mar 30, 2023
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Life on Earth comes in a beautiful assortment of different shapes, sizes and colors, thanks to genetic mutations. Some mutations are beneficial, some are perilous, and some don't do much of anything. Every person has around ...
Mar 30, 2023
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Why do cancer immunotherapies work so extraordinarily well in a minority of patients, but fail in so many others? By analyzing the role of neutrophils, immune cells whose presence usually signals treatment failure, scientists ...
Mar 30, 2023
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Brain development consists of a sequence of coordinated steps, which are mainly instructed by our genes. During these steps, the proper positioning and functionality of nerve cells in the brain (neurons) are critical—nonfunctional ...
Mar 29, 2023
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Just like pruning a tree helps promote proper growth, the brain uses synaptic pruning to get rid of unnecessary connections between its cells. However, when this normal process, which occurs between early childhood and adulthood, ...
Mar 23, 2023
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