Journal of Clinical Investigation

Oncology & Cancer

Novel regulator of immune evasion in cancer identified

Northwestern Medicine investigators have identified a previously unknown regulator of tumor immune evasion, which may help improve the efficacy of current and future anti-tumor immunotherapies, according to recent findings ...

Diseases, Conditions, Syndromes

Intriguing insights uncovered for two rare heart muscle diseases

Advancements in the study of two rare heart conditions—peripartum cardiomyopathy (PPCM), and dilated cardiomyopathy (DCM)—contributed by researchers at the Perelman School of Medicine at the University of Pennsylvania ...

Oncology & Cancer

Novel therapeutic target overcomes resistance to radiation therapy

A new study finds that radiation therapy (RT) suppresses a key protein called bone morphogenetic protein and activin membrane-bound inhibitor (BAMBI) and activates immune suppressive cells. These effects dampen the capacity ...

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