Journal of Clinical Investigation

Alzheimer's disease & dementia

Beige fat 'indispensable' in protecting the brain from dementia

Beige is considered a calming paint color, and scientists have new evidence that beige fat has a similar impact on the brain, bringing down the inflammation associated with the more common white fat and providing protection ...

Cardiology

Re-purposed drugs could reverse blood vessel damage in diabetes

Drugs that were developed to treat Alzheimer's Disease could be re-purposed to prevent—or even reverse—the damage done to the blood vessels in people who are obese or suffer from type 2 diabetes, according to new research.

Medical research

A new drug target for kidney disease

Despite nearly two million people dying of acute kidney injury every year, and tens of millions more needing treatment, no effective drug treatment for the condition is available. Furthermore, most acute kidney injury patients ...

Oncology & Cancer

Researchers identify genetic 'seeds' of metastatic breast cancer

Breast cancer is the second leading cause of cancer death in women in the United States, with most deaths caused by the cancer spreading beyond the breast. In a new study, University of North Carolina Lineberger Comprehensive ...

Oncology & Cancer

Brain cancer clinical trial gives hope to patients

Queensland researchers have found that patients who received a cellular immunotherapy for the deadly brain cancer glioblastoma multiforme (GBM) in a clinical trial on average survived longer than would have been expected ...

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