Journal of Experimental Medicine

Tumor blood vessels prevent the spread of cancer cells

A lack of the protein endoglin in the blood vessels of tumour-bearing mice enables the spread of daughter tumours, according to researchers at Karolinska Institutet and Lund University in Sweden in a study published in the ...

Feb 11, 2013
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The skin aging regulator

Despite progress in regenerative medicine, with age, the skin loses its properties in an irreversible manner. The ATIP-Avenir team "Epidermal homeostasis and tumorigenesis" directed by Chloé Féral, an Inserm ...

Jan 22, 2013
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Surviving sepsis with LECT2

Failure to launch an adequate immune response may be at the root of septic shock, according to a study published in The Journal of Experimental Medicine on December 17th.

Dec 17, 2012
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Gene knockout stops immune cell development

(Medical Xpress)—Researchers at the Wellcome Trust Sanger Institute have identified the key gene in ensuring that our immune defences develop infection-fighting cells. No cells of the adaptive immune system ...

Dec 11, 2012
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(Antibody) orientation matters

The orientation of antibody binding to bacteria can mean life or death to the bug, according to a study published in The Journal of Experimental Medicine on December 10th. These findings may help explain why these bacter ...

Dec 10, 2012
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Cocktail boosts immune cells in fighting cancer

Natural killer cells, as part of the body´s immune system, can effectively fight cancer. Unfortunately, they quickly lose their aggressiveness and hence are unable to reject solid tumors. Scientists from the German Cancer ...

Dec 06, 2012
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Dermatitis could be suppressed as it develops

Excessive immune reactions against the body's own skin cells can lead to painful and even chronic dermatitis. An international team of researchers at the MedUni Vienna, the MedUni Graz and the Salk Institute ...

Nov 09, 2012
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Mouse model exposes a new type of T cell to target melanoma

Cancers arise in the body all the time. Most are nipped in the bud by the immune response, not least by its T cells, which detect telltale molecular markers—or antigens—on cancer cells and destroy them before they grow ...

Oct 24, 2012
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Helping ex-smokers resist the urge

A new inhibitor helps previously nicotine-addicted rats stay on the wagon, according to a study published on October 22nd in the Journal of Experimental Medicine.

Oct 22, 2012
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