Journal of Experimental Medicine
How Parkinson's disease starts and spreads
Injection of a small amount of clumped protein triggers a cascade of events leading to a Parkinson's-like disease in mice, according to an article published online this week in the Journal of Experimental Medicine.
Parkinson's & Movement disorders
Apr 16, 2012 |
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Potential gene therapy for patients with rare disease
Australian scientists have discovered that a biological phenomenon known as ‘somatic reversion’, when an abnormal gene spontaneously becomes normal again, explains why some patients with a rare genetic ...
Medical research
Apr 12, 2012 |
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Getting down to the heart of the (gray) matter to treat Parkinson's disease
An agent under consideration for use in PET imaging combats neuronal death to relieve Parkinsonian symptoms in animal models, according to a study published on April 2nd in the Journal of Experimental Medicine.
Parkinson's & Movement disorders
Apr 02, 2012 |
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New memory for HIV patients
The hallmark loss of helper CD4+ T cells during human immunodeficiency virus (HIV) infection may be a red herring for therapeutics, according to a study published on March 26th in the Journal of Experimental Medicine.
HIV & AIDS
Mar 26, 2012 |
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Breaking the backbone of triple-negative breast cancers
Putting the brakes on an abundant growth-promoting protein causes breast tumors to regress, according to a study published on March 19th in the Journal of Experimental Medicine.
Cancer
Mar 19, 2012 |
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Lasting T cell memories
The generation of new memories in the human immune system doesn't come at the cost of old ones, according to a study published on March 5th in the Journal of Experimental Medicine.
Immunology
Mar 05, 2012 |
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A culprit behind brain tumor resistance to therapy
Persistent protein expression may explain why tumors return after therapy in glioblastoma patients, according to a study published on March 5th in the Journal of Experimental Medicine.
Cancer
Mar 05, 2012 |
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Drug combination domino effect destroys pancreatic cancer cells
(Medical Xpress) -- Cancer Research UK scientists have revealed how a combination of two very different drugs – currently being tested in clinical trials – amplifies the destruction of pancreatic cancer cells, according ...
Cancer
Feb 22, 2012 |
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Traitorous immune cells promote sudden ovarian cancer progression
Aggressive ovarian tumors begin as malignant cells kept in check by the immune system until, suddenly and unpredictably, they explode into metastatic cancer. New findings from scientists at The Wistar Institute demonstrate ...
Cancer
Feb 20, 2012 |
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How autoreactive T cells slip through the cracks
Immune cells capable of attacking healthy organs "see" their targets differently than do protective immune cells that attack viruses, according to work published online this week in the Journal of Experimental Medicine.
Medical research
Feb 06, 2012 |
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Selectively inhibiting PKM2 starves cancer cells
Crippling a protein that allows cancer cells to grow when oxygen is scarce causes tumors to regress, according to a study published online on January 23 in the Journal of Experimental Medicine.
Cancer
Jan 23, 2012 |
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A single therapy slows multiple cancers
Targeting a single protein can help fight both breast cancers and leukemias, according to two reports published online on January 23 in the Journal of Experimental Medicine.
Cancer
Jan 23, 2012 |
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Researchers identify pivotal immune cell in Type 1 diabetes in humans
(Medical Xpress) -- Researchers at the La Jolla Institute for Allergy & Immunology have proven – for the first time in human tissues -- the specific immune system T cells which trigger the destruction of type 1 diabetes ...
Immunology
Jan 12, 2012 |
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Scientists identify a novel therapy with potential for treating Parkinson's disease
Scientists at the University of Cambridge have made a significant step in the development of a novel therapy that could one day help to slow down, or even halt, the damage caused by Parkinson’s disease ...
Medical research
Dec 22, 2011 |
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Genetic diversity: Crucial for our survival in many ways
(Medical Xpress) -- Thanks to the sequencing of the 27 known human interferon genes, researchers from the Institut Pasteur and the CNRS reconstruct the genetic history of these proteins so central for our immune system, and ...
Genetics
Dec 20, 2011 |
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