Neural signature of affiliative experience identified in human brain

September 4, 2012

How would you respond if someone told you that you have a very dedicated son and that he got the scholarship he most wished? Or that the company you worked for made great profits and you will receive a good salary raise?

While the former situation represents a positive affiliative experience the latter is a non-affiliative one, and that, according to a paper published in tomorrow's issue of the Journal of Neuroscience, can make all the difference to the way your brain responds.

Affiliative experiences are inherent to humans and other mammals. It has been known for some time that sustain by showing affiliative behavior, which promotes group cohesion and cooperation among members. Previous studies done in animals have pointed to specific regions in the brain involved in these behaviors.

In humans, the challenge has been to show how affiliative experience modulates and to distinguish these experiences from non-affiliative negative and positive emotions such as fear and sorrow or joy and pride.

In a paper entitled "A neural signature of affiliative emotion in the human septohypothalamic area" and published this week in the , a group led by Dr Jorge Moll at the Cognitive and Behavioral Neuroscience Unit at D'Or Institute, in Rio de Janeiro, Brazil, compared to affiliative and non-affiliative social scenarios associated with either positive or .

The group, which also includes Dr Roland Zahn at the University of Manchester and the Manchester Academic Health Sciences Center at the School of in the United Kingdom, and other researchers from the Federal University of Rio de Janeiro, the State University of and the Federal University of ABC, in Brazil, succeeded in designing an experimental set up using functional MRI in which affiliative experiences could be differentiated from that did not involve affiliation.

By presenting each of the 27 healthy volunteers with 280 of five different types (affiliative positive, affiliative negative, non-affiliative positive, non-affiliative negative, and neutral) consisting each of two short sentences, the group asked each participant to rate the amount of positive or negative emotional experience associated with each scenario. When faced with scenarios such as "You were distracted and lost your young child in the park" (affiliative negative) or "You were blamed for a problem that was not your fault and lost your job" (non-affiliative negative) each participant was asked to rate the scenario using a scale ranging from very unpleasant to neutral to very pleasant. In addition, participants evaluated each scenario according to its degree of affiliation by rating the level of care or tenderness involved.

"Our study shows that the septal/preoptic-anterior hypothalamic area is the key region engaged by affiliative stimuli," says Dr Moll. The study also shows that this response was irrespective of whether the stimuli were emotionally positive or negative.

"The septal/preoptic-anterior hypothalamic area has been previously indicated as involved in attachment-related behaviors in other species but only now have we been able to show the existence of a neural signature of human affiliative experience," says Dr Ricardo de Oliveira-Souza, who also participated in the study.

The identification of the brain mechanisms associated with affiliative experiences is crucial for a deeper understanding of how our emotions are triggered, especially those that connect us to our loved ones. Additionally, these findings may bear direct implications for neuropsychiatric conditions in which affiliative experiences and behaviors are impaired, such as post-partum depression, psychopathy and attachment disorders.

Explore further: Women anticipate negative experiences differently to men

Related Stories

Recommended for you

New mechanism discovered behind infant epilepsy

September 3, 2015

Scientists at Karolinska Institutet and Karolinska University Hospital in Sweden have discovered a new explanation for severe early infant epilepsy. Mutations in the gene encoding the protein KCC2 can cause the disease, hereby ...

Neuron responsible for alcoholism found

September 2, 2015

Scientists have pinpointed a population of neurons in the brain that influences whether one drink leads to two, which could ultimately lead to a cure for alcoholism and other addictions.

Scientists see motor neurons 'walking' in real time

September 2, 2015

When you're taking a walk around the block, your body is mostly on autopilot—you don't have to consciously think about alternating which leg you step with or which muscles it takes to lift a foot and put it back down. That's ...

Deciphering the olfactory receptor code

August 31, 2015

In animals, numerous behaviors are governed by the olfactory perception of their surrounding world. Whether originating in the nose of a mammal or the antennas of an insect, perception results from the combined activation ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.