HIV-1 vaccine development: Pinning down a moving target

A major problem researchers have faced in attempting to develop a vaccine for HIV is that the virus mutates incredibly quickly, which means that its antigens—the target molecules of a vaccine—are moving targets. ...

The human body can produce powerful antibodies that shield cells in the laboratory against infection by an array of HIV strains. In people, however, recent research shows that these broadly neutralizing antibodies are not ...

HIV tires out the cells that produce virus-fighting proteins known as antibodies, according to a human study that will be published online July 14 in the Journal of Experimental Medicine.

Weill Cornell Medical College scientists say they've determined a protein produced by HIV infected cells prevents immune B cells from producing antibodies.

Recent studies have shown that HIV causes a vigorous and prolonged immune response that eventually leads to the exhaustion of key immune system cells--CD4+ and CD8+ T-cells--that target HIV. These tired cells become less ...

People with HIV are more likely to keep their scheduled medical appointments—and their disease under control—if they feel their physician listens, explains things clearly and knows them as a person, not just a "case," ...

Secretary of State John Kerry on Tuesday hailed the 10th anniversary of a US program to battle AIDS, saying it has helped one million babies be born disease-free to mothers infected with HIV.

Age disparities exist in the continuum of care for patients with the human immunodeficiency virus (HIV) with people younger than 45 years less likely to be aware of their infection or to have a suppressed viral load, according ...

HIV prevention programs for female sex workers in India reduce rates of syphilis, HIV and other sexually transmitted infections (STIs), a University of Toronto study has found.

Secretary-General Ban Ki-moon says the overall U.N. goal of halting and reversing the spread of AIDS will be met by the target date of 2015.

In India most people who are HIV positive don't know it, yet testing and treatment are relatively cheap and available. It would therefore meet international standards of cost-effectiveness—and save millions of lives for ...