Topical anesthetics effective for premature ejaculation

April 12, 2013
Topical anesthetics effective for premature ejaculation
Topical anesthetic agents seem to be effective and are generally well tolerated for patients with premature ejaculation, according to a review published in the April issue of Urology.

(HealthDay)—Topical anesthetic agents seem to be effective and are generally well tolerated for patients with premature ejaculation (PE), according to a review published in the April issue of Urology.

Chunxiao Pu, from Sichuan University in China, and colleagues conducted a systematic literature review and meta-analysis including data from eight eligible randomized controlled trials to assess the efficacy of topical on intravaginal ejaculatory latency time (IELT).

In the pooled analysis, the researchers found that IELT was significantly improved in the topical anesthetic agent group versus the . In subgroup analyses, significant improvements were observed in the domains of ejaculatory control, sexual satisfaction, and distress in the Index of questionnaire. Compared with the placebo group, the topical anesthesia group experienced a significantly higher overall incidence of adverse events (random-effect model; relative risk, 4.28), although almost all adverse events were mild and transient.

"Considering these results, on-demand topical anesthetic agents could be considered a treatment option for patients with lifelong PE," write the authors. "Large, multicenter, prospective should be anticipated in the future to confirm the safety and efficacy of topical anesthetic agents."

Explore further: Non-cocaine, topical anaesthetics can kill pain when repairing skin wounds

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Cold-air anesthesia reduces pain of laser treatment

June 22, 2012

(HealthDay) -- In ablative fractionated carbon-dioxide (CO2) laser treatment for photoaging, cold-air anesthesia used in conjunction with topical anesthesia reduces pain significantly more than topical anesthesia alone, according ...

Sequential oral, topical tacrolimus benefits dermatitis

September 20, 2012

(HealthDay)—Sequential therapy with oral tacrolimus and topical tacrolimus may be an effective treatment for severe atopic dermatitis (AD), according to a pilot study published in the October issue of the Journal of the ...

Single topical ivermectin head lice treatment very effective

November 2, 2012

(HealthDay)—A single 10-minute, at-home treatment with topical ivermectin lotion eliminates head lice infestations in nearly all patients by the next day, according to a study published in the Nov. 1 issue of the New England ...

Recommended for you

Monkeys in Asia harbor virus from humans, other species

November 19, 2015

When it comes to spreading viruses, bats are thought to be among the worst. Now a new study of nearly 900 nonhuman primates in Bangladesh and Cambodia shows that macaques harbor more diverse astroviruses, which can cause ...

One-step test for hepatitis C virus infection developed

November 14, 2015

UC Irvine Health researchers have developed a cost-effective one-step test that screens, detects and confirms hepatitis C virus (HCV) infections. Dr. Ke-Qin Hu, director of hepatology services, will present findings at the ...

Computer model reveals deadly route of Ebola outbreak

November 10, 2015

Using a novel statistical model, a research team led by Columbia University's Mailman School of Public Health mapped the spread of the 2014-2015 Ebola outbreak in Sierra Leone, providing the most detailed picture to date ...


Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.