A rise in early diagnosis of prostate cancer

(Medical Xpress)—Over the last two decades, incremental gains have been made in the number of men given early diagnosis of prostate cancer, and the way they are treated, a Victorian study found.

Using the Victorian Prostate Cancer Registry, Dr Sue Evans, a senior research fellow in the Department of Epidemiology and at Monash University, and co-authors, conducted a review of patterns of care for men diagnosed with prostate cancer in Victoria from 2008 to 2011.

Published today in the Medical Journal of Australia, the study included 2724 men from 11 public and six private Victorian hospitals. The men were followed up 12 months after diagnosis.

The data was then compared with the numbers from a study of the management of men with prostate cancer who were diagnosed in 1993.

The authors found a drop in the average blood level of the prostate-specific antigen (PSA) at diagnosis compared with the 1993 study, suggesting much earlier diagnosis.

Most patients (93 per cent) were diagnosed with localised disease (cancers confined to the ), and nearly half of them were at intermediate risk of .

A year after diagnosis, 41 per cent of men at low risk of progression had received no active treatment, while 55 per cent at intermediate risk had undergone a and 12 per cent at high risk had received no active treatment.

Similarly, the percentage of men receiving no active treatment declined from 36 per cent in 1993 to 23 per cent in 2008–2011.

"Our finding that 71 per cent of men received surgery, radiotherapy and/or brachytherapy contrasts with results of the 1993 Victorian study, in which 25 per cent of men received initial treatment with curative intent," Dr Evans said.

"There has also been a dramatic 'stage migration' towards earlier diagnosis of —the vast majority of men in our study were diagnosed with localised disease and only 3.3 per cent were diagnosed with metastatic disease (spread of a cancer throughout the body)."

Men aged over 75 years were more than 10 times as likely not to receive active treatment as those younger than 55 years.

Related Stories

Prostate cancer may be deadlier for the uninsured

date May 07, 2013

(HealthDay)—Men who are uninsured or underinsured get advanced prostate cancer at nearly four times the national average and don't survive as long as other men with advanced disease, a new study says.

Recommended for you

Spicy treatment the answer to aggressive cancer?

date Jul 03, 2015

It has been treasured by food lovers for thousands of years for its rich golden colour, peppery flavour and mustardy aroma…and now turmeric may also have a role in fighting cancer.

Cancer survivors who smoke perceive less risk from tobacco

date Jul 02, 2015

Cancer survivors who smoke report fewer negative opinions about smoking, have more barriers to quitting, and are around other smokers more often than survivors who had quit before or after their diagnosis, according to a ...

Melanoma mutation rewires cell metabolism

date Jul 02, 2015

A mutation found in most melanomas rewires cancer cells' metabolism, making them dependent on a ketogenesis enzyme, researchers at Winship Cancer Institute of Emory University have discovered.

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.