New treatment for brittle bone disease found

New treatment for brittle bone disease found

A new treatment for children with brittle bone disease has been developed by the University of Sheffield and Sheffield Children's Hospital.

The study of the new treatment for children with the fragile bone disease Osteogenesis Imperfecta was published this week in the world's leading general medical journal, The Lancet.

This is the first study to clearly demonstrate that the use of the medicine risedronate can not only reduce the risk of fracture in children with brittle bones but also have rapid action - the curves for begin to diverge after only 6 weeks of treatment.

Nick Bishop, Professor of Paediatric Bone Disease at the University of Sheffield, said: "We wanted to show that the use of risedronate could significantly impact on children's lives by reducing fracture rates - and it did.

"The fact that this medicine can be given by mouth at home (other similar medicines are given by a drip in hospital) makes it family-friendly."

The study, funded by the Alliance for Better Bone Health, trialled children with Osteogenesis Imperfecta aged 4-15 years and showed that oral reduced the risk of first and recurrent clinical fractures and that the drug was generally well tolerated.

More information: To read the published article in The Lancet, titled Risedronate in children with osteogenesis imperfecta: a randomised, double-blind, placebo-controlled trial, visit The Lancet. www.thelancet.com/journals/lan… 3%2961091-0/fulltext

add to favorites email to friend print save as pdf

Related Stories

Gene discoveries give hope against 'Brittle bone' disease

May 08, 2013

(HealthDay)—Mutations in a gene involved in bone development appear to cause certain severe forms of bone loss, a finding that could lead to new therapies for the common bone-thinning disorder osteoporosis, ...

Recommended for you

Ebola isolation at US base 'pretty much vacation'

9 hours ago

With plenty of flat screen TVs, game nights and even an outdoor fire pit, life in isolation for members of the U.S. military who have returned from the Ebola mission in West Africa can look a lot like summer camp.

Chinese-built Ebola center dedicated in Liberia

13 hours ago

China, one of the first countries to send aid to battle Ebola in West Africa, ramped up the assistance significantly Tuesday by opening a 100-bed treatment center in Liberia as rows of uniformed Chinese army ...

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.