Study links depression to arterial stiffness during stress

by Melva Robertson
Study links depression to arterial stiffness during stress
Depressive symptoms significantly increased arterial stiffness induced by mental stress, but had no effect on arterial stiffness with exercise.

(Medical Xpress)—According to a study by researchers at Emory's Rollins School of Public Health, symptoms of depression are associated with an increase in arterial stiffness induced by mental stress. Arterial stiffness indicates a reduced capability of an artery to expand and contract in response to blood pressure change. It is an important indicator of future cardiovascular events and has been shown to worsen during stressful conditions.

The Emory team studied 81 young and middle-aged patients who had a recent heart attack. All subjects underwent an acute emotional stress task in addition to a standard exercise stress test. The researchers measured with a Pulse Wave Velocity system, at rest and 60 minutes after stress, and calculated stress-induced changes in arterial stiffness.

Depressive symptoms significantly increased arterial stiffness induced by , but had no effect on arterial stiffness with exercise. These results were not explained by differences in or heart disease severity.

"Depression may cause worsened arterial stiffness with , but not with exercise," says lead author Pratik Pimple, MBBS, from Emory's Rollins School of Public Health.

"These findings may help explain why depression is linked to adverse cardiovascular outcomes," adds Viola Vaccarino, MD, PhD, the study director and the Wilton Looney Chair of Cardiovascular Research in the Department of Epidemiology at Rollins.

add to favorites email to friend print save as pdf

Related Stories

In elderly, hardening of arteries linked to plaques in brain

Oct 16, 2013

Even for elderly people with no signs of dementia, those with hardening of the arteries are more likely to also have the beta-amyloid plaques in the brain that are a hallmark of Alzheimer's disease, according to a study published ...

Metabolic syndrome linked to arterial stiffness in CKD

Jun 04, 2012

(HealthDay) -- For patients with chronic kidney disease (CKD), those with metabolic syndrome (MetS) have increased arterial stiffness but no increase in endothelial dysfunction, compared to those without MetS, ...

Recommended for you

Cerebrovascular reserve-based strategy is cost-effective

Jan 29, 2015

(HealthDay)—A decision rule based on assessment of cerebrovascular reserve (CVR) seems to be cost-effective for prevention of stroke in asymptomatic patients with carotid artery stenosis, according to a ...

New hypertension guidelines could save lives and money

Jan 28, 2015

Full implementation of new hypertension guidelines could prevent 56,000 cardiovascular disease events (mostly heart attacks and strokes) and 13,000 deaths each year, without increasing overall health care costs, an analysis ...

Manchester United's rising stars revolutionize heart health

Jan 28, 2015

A unique research project to identify the effects of exercise on young hearts has been announced today [Wednesday 28 January 2015]. Manchester United's Academy players are being put through their paces having their hearts ...

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.