Maths plus medicine equals new imaging innovation

May 8, 2014
Maths plus medicine equals new imaging innovation
Medical undergraduate Charles Baker has developed a mathematical model to improve liver imaging methods. Inset: An image of a liver with five lesions.

A medical student from The University of Queensland has applied his background in mathematics to the field of nuclear medicine to improve liver imaging methods, which may improve diagnosis time and possibly save patients undergoing unnecessary surgery.

Third year medical undergraduate Charles Baker has developed a mathematical model that can be programmed into existing to enhance images of patients' livers.

Mr Baker said the model uses variables specifically relating to the structure of the to help nuclear medicine specialists better differentiate between healthy and damaged liver tissue.

"This means we can improve the output of existing scanning equipment to provide better image quality for specialists," Mr Baker said.

"The resulting images demonstrate higher contrast between healthy liver tissue and unhealthy , such as malignant tumours."

The mathematical model is undergoing clinical appraisal in the Nuclear Medicine Department at the Royal Brisbane and Women's Hospital (RBWH) and Mr Baker said initial feedback had been encouraging.

"We hope that practical testing of the model across a larger number of images will help identify how it will improve clinical decision-making and patient outcomes."

"For example, scans using the may help to more clearly identify areas of dead tumour tissue and active tumour tissue. Clinicians can use this information to better target treatments."

The improved contrast would also help specialists to more easily interpret scans, saving time.

"Most importantly, the higher contrast scans might save people from undergoing unnecessary surgical procedures," Mr Baker said.

He is now working on mathematical models to improve imaging in other parts of the body, such as the brain.

Explore further: Restoring what's lost: Uncovering how liver tissue regenerates

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