Survival up with successful PCI to a chronic total occlusion

July 17, 2014
Survival up with successful PCI to a chronic total occlusion

(HealthDay)—For patients with chronic total occlusion, successful percutaneous coronary intervention (PCI) is associated with improved long-term survival, according to a study published in the July 22 issue of the Journal of the American College of Cardiology.

Sudhakar George, M.D., from the Brighton and Sussex University Hospitals in the United Kingdom, and colleagues compared outcomes for with a successful versus unsuccessful PCI to a chronic total occlusion. Data were collected from the U.K. Central Cardiac Audit Database for all chronic total occlusion PCI cases carried out in England and Wales from 2005 through 2009. The cohort included 13,443 patients (78.8 percent male; mean age, 63.5 years) who underwent 14,439 chronic total occlusion procedures.

The researchers found that PCI was successful in 70.6 percent of the cases. Successful PCI of at least one chronic total occlusion correlated with improved survival during 2.65 years of follow-up (hazard ratio, 0.72; P < 0.001). Compared with partial revascularization or failed revascularization, complete revascularization correlated with improved survival (hazard ratios, 0.70 [P = 0.002] and 0.61 [P < 0.001], respectively).

"Successful chronic total occlusion PCI was associated with improved long-term ," the authors write. "The improvement was greatest in patients when complete revascularization was achieved."

Several authors disclosed financial ties to the pharmaceutical and medical device industries.

Explore further: Study examines multivessel mortality rates

More information: Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Related Stories

Study examines multivessel mortality rates

December 29, 2011

(Medical Xpress) -- A new study led by University at Albany School of Public Health Distinguished Professor Emeritus Edward L. Hannan finds a link between higher mortality rates and incomplete revascularization procedures ...

Increased stroke risk at 30-days post-CABG versus PCI

August 21, 2012

(HealthDay) -- The risk of stroke at 30 days is significantly higher in patients who undergo coronary revascularization with coronary artery bypass graft (CABG) surgery compared to those who undergo percutaneous coronary ...

Clinical outcomes similar for elderly with PCI, CABG

August 27, 2013

(HealthDay)—For older patients with unprotected left main coronary artery disease, clinical outcomes are similar with percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG), according to research ...

Higher operator volume linked to better PCI outcomes

June 19, 2014

(HealthDay)—Higher individual operator percutaneous coronary intervention (PCI) volume is associated with better outcomes, according to a review published online June 17 in Circulation: Cardiovascular Quality and Outcomes.

Recommended for you

No new heart muscle cells in mice after the newborn period

November 5, 2015

A new study from Sweden's Karolinska Institutet shows that new heart muscle cells in mice are mainly formed directly after birth. After the neonatal period the number of heart muscle cells does not change, and A new study ...

Nanotechnology could spur new heart treatment

October 29, 2015

A new nanoparticle developed by University of Michigan researchers could be the key to a targeted therapy for cardiac arrhythmia, a condition that causes the heart to beat erratically and can lead to heart attack and stroke.


Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.