Broad Institute of MIT and Harvard

Compounds point the way to cancer's dependencies

The Broad Institute's Center for the Science of Therapeutics today announced the launch of its Cancer Therapeutics Response Portal (CTRP; http://www.broadinstitute.org/ctrp/) – a critical resource for advancing the discovery of potential ...

Aug 29, 2013
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LITE illuminates new way to study the brain

For core faculty member Feng Zhang's lab, nature offers up the raw ingredients needed to control brain cells and understand the brain's wiring. Since joining the Broad Institute and McGovern Institute for ...

Jul 24, 2013
popularity 4.6 / 5 (5) | comments 1 | with audio podcast

Following the footprints of positive selection

For decades, the human genome could only tell us what we already suspected about the evolution of certain traits. Researchers were able to trace the genetic origin stories of lactose tolerance (as opposed ...

Feb 15, 2013
popularity 5 / 5 (1) | comments 0 | with audio podcast

Kidney disease mutations found in a genomic blind spot

(Medical Xpress)—Advances in DNA sequencing technology during the past decade have given scientists powerful tools to peer into the genomes of humans and other species. Despite the efficiency and sophistication ...

Feb 11, 2013
popularity 5 / 5 (1) | comments 0 | with audio podcast

Scientists investigate inherited causes of autism

Autism spectrum disorders (ASD) are among the most heritable of all neuropsychiatric conditions. Yet, most genetic links to ASD found in recent years have involved de novo mutations, which are not passed from parent to child, ...

Feb 04, 2013
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1,092 genomes and counting

Focusing on fine features in order to see "the big picture" seems almost counterintuitive, but that is exactly what is happening in the field of genomics. Researchers are sequencing human genomes, cataloging ...

Nov 16, 2012
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New breast cancer genetic alterations discovered

Breast cancer is not a single disease, but a collection of diseases with dozens of different mutations that crop up with varying frequency across different breast cancer subtypes. Deeper exploration of the genetic changes ...

Jun 20, 2012
popularity not rated yet | comments 0 | with audio podcast