Scientists at Cold Spring Harbor Laboratory (CSHL) have discovered that one of the most common genetic alterations in autism -- deletion of a 27-gene cluster on chromosome 16 -- causes autism-like features. ...
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The work of a team of scientists at Cold Spring Harbor Laboratory (CSHL) led by Professor Nicholas Tonks FRS, suggests a way to overcome one of the major technical obstacles preventing a leading therapeutic target for diabetes ...
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A team of neuroscientists at Cold Spring Harbor Laboratory (CSHL) has succeeded in creating what amounts to a GPS system for locating and tracking a vital class of brain cells that until now has eluded comprehensive identification, ...
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The digestive system is home to a myriad of viruses, but how they are involved in health and disease is poorly understood. In a study published online today in Genome Research, researchers have investigated the dynamics of vir ...
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We know from experience that particular smells are almost inseparable in our minds with memories, some vague and others very specific. The smell of just-baked bread may trigger an involuntary mental journey, even if for a ...
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Alzheimer's disease and frontotemporal lobar degeneration (FTLD) are two of the most prevalent forms of neurodegenerative disorders. In a study published online today in Genome Research, researchers have analyzed changes in gen ...
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Of the 250,000 American men who will be diagnosed with prostate cancer this year, very few of them—about 1 percent—will develop lethal, metastatic disease. Finding a way to distinguish between this small cohort ...
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Scientists at Cold Spring Harbor Laboratory (CSHL) and five other institutions have used an unconventional approach to cancer drug discovery to identify a new potential treatment for acute myeloid leukemia (AML). As reported ...
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A team of scientists at Cold Spring Harbor Laboratory (CSHL) has laid bare the mechanism behind a phenomenon called oncogene addiction in mice suffering from a form of leukemia that mimics acute myelogenous leukemia (AML) ...
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Neuroscientists have long pioneered the use of new visualization techniques. Imaging in Neuroscience: A Laboratory Manual continues that tradition by presenting an outstanding collection of methods for vi ...
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Researchers at Cold Spring Harbor Laboratory (CSHL) have identified an enzyme that appears to be a significant regulator of breast cancer development. Called PTPN23, the enzyme is a member of a family called protein tyrosine ...
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Today, most scientists use the term "mutation" to describe a change in an individual gene -- more precisely a minute alteration of its DNA. But the term has also achieved a powerful presence in popular culture, ...
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A clinically extensive and mathematically powerful study of 1000 families with one autistic child and one unaffected sibling has validated a controversial theory of autism's complex genetic causation. The study for the first ...
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Malignant melanoma is a highly aggressive and notoriously chemoresistant form of cancer. In a new paper, Ohanna et al. reveal that anti-melanoma drugs may, paradoxically, induce a senescence-associated secretory profile ("secretome") ...
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A new study from Cold Spring Harbor Laboratory (CSHL) offers an explanation for why our brains produce fewer and fewer neurons with age, a phenomenon thought to underlie age-related cognitive decline. The ...
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