Helmholtz Association of German Research Centres
New animal model gives insights into mechanisms of Parkinson's disease pathogenesis
In Parkinson's disease, the protein "alpha-synuclein" aggregates and accumulates within neurons. Specific areas of the brain become progressively affected as the disease develops and advances. The mechanism underlying this ...
Parkinson's & Movement disorders
9 hours ago |
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Signs of motor disorders can appear years before disease manifestation
It is known that signs of neurological disorders such as Alzheimer's and Huntington's disease can appear years before the disease becomes manifest; these signs take the form of subtle changes in the brain and behavior of ...
Neuroscience
May 22, 2013 |
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Posttraumatic stress disorder associated with type 2 diabetes
The presence of posttraumatic stress disorder is significantly associated with the development of type 2 diabetes. This is the finding of scientists from the Helmholtz Zentrum München and the University Hospital Gießen ...
Psychology & Psychiatry
May 16, 2013 |
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How individuality develops? Experience leads to the growth of new brain cells
How do organisms evolve into individuals that are distinguished from others by their own personal brain structure and behavior? Scientists in Dresden, Berlin, Münster, and Saarbrücken have now taken a decisive step towards ...
Neuroscience
May 09, 2013 |
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Serotonin mediates exercise-induced generation of new neurons
Mice that exercise in running wheels exhibit increased neurogenesis in the brain. Crucial to this process is serotonin signaling. These are the findings of a study by researchers at the Max Delbrück Center ...
Neuroscience
May 13, 2013 |
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Individual efficacy of chemotherapies
The function of the mitochondria – also defined as "power plants" within the cells – is essential as to whether, and how, some chemotherapeutic agents take effect in tissue. Scientists at the Helmholtz ...
Cancer
May 10, 2013 |
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Metastasis stem cells in the blood of breast cancer patients discovered
Individual cancer cells that break away from the original tumor and circulate through the blood stream are considered responsible for the development of metastases. These dreaded secondary tumors are the ...
Cancer
Apr 22, 2013 |
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Researchers find controlling element of Huntington's disease
A three molecule complex may be a target for treating Huntington's disease, a genetic disorder affecting the brain. This finding by an international research team including scientists from the German Center for Neurodegenerative ...
Diseases, Conditions, Syndromes
Feb 26, 2013 |
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'Healthier hormones' through diet and exercise
Weight loss—by dietary changes alone or combined with physical exercise—has a positive impact on the production of adipose tissue hormones: Adipose tissue produces less leptin but, instead, more adiponectin, which counteracts ...
Health
Mar 07, 2013 |
3.5 / 5 (2) |
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Evolution in the antibody factory: How immune cells are able to advance their own evolution
Immune system B cells play a crucial role in the defence of pathogens; when they detect such an intruder, they produce antibodies that help to combat the enemy. They concurrently and continuously improve ...
Immunology
Mar 11, 2013 |
4.7 / 5 (3) |
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Misplaced molecules: New insights into the causes of dementia
A team of German and Belgian researchers has succeeded in gaining new insights into the causes of certain movement disorders and forms of dementia. Scientists including Bettina Schmid and Christian Haass from the German Center ...
Neuroscience
Mar 01, 2013 |
3.7 / 5 (3) |
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GI tract bacteria may protect against autoimmune disease
Early life exposure to normal bacteria of the GI tract (gut microbes) protects against autoimmune disease in mice, according to research published on-line in the January 17 edition of Science. The study ...
Immunology
Jan 17, 2013 |
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Translation error tracked in the brain of dementia patients
In certain dementias silent areas of the genetic code are translated into highly unusual proteins by mistake. An international team of scientists including researchers from the German Center for Neurodegenerative ...
Neuroscience
Feb 07, 2013 |
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Exposure to everyday noise influences heart rate variability
(Medical Xpress)—Exposure to noise, for example from road traffic, may adversely affect the cardiovascular system. Until now, underlying mechanisms linking noise to elevated cardiovascular risk have rarely been explored ...
Health
May 02, 2013 |
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The molecular basis of touch sensation: New function of a well-known gene identified
A gene known to control lens development in mice and humans is also crucial for the development of neurons responsible for mechanosensory function, as neurobiologists of the Max Delbrück Center for Molecular Medicine ...
Genetics
Feb 21, 2012 |
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