A mysterious inflammatory disease has been afflicting a Flemish family for three generations, causing severe skin lesions, fevers, pain and exhaustion. This disease, which previously had no known cause or cure, has now been ...
Mar 30, 2016
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5
Led by Jean-Christophe Marine (VIB-KU Leuven), a team of researchers has tracked down the cellular origin of cutaneous melanoma, the deadliest form of skin cancer. The team was surprised to observe that these very aggressive ...
Oct 12, 2017
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205
The brain consists of a large collection of interconnected neurons. How complex patterns of neuronal cells grow into functioning circuits during development has fascinated researchers for decades. A team of scientists at ...
May 3, 2019
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249
VIB researchers have developed a mouse model for Charcot-Marie-Tooth (CMT) neuropathy, a hereditary disease of the peripheral nervous system. They also found a potential therapy for this incurable disease. The treatment ...
Aug 2, 2011
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0
A collaborative study has identified a new molecular mechanism causing rheumatoid arthritis. The researchers found that death of macrophages, an immune cell type, can trigger the disease. Moreover, they discovered how the ...
May 14, 2019
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199
Neuroscientist Patrik Verstreken, associated with VIB and KU Leuven, succeeded in undoing the effect of one of the genetic defects that leads to Parkinson's using vitamin K2. His discovery gives hope to Parkinson's patients. ...
May 11, 2012
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1
Chronic inflammatory rheumatic diseases such as rheumatoid arthritis (RA) and spondylo-arthritis (SpA) are chronic, disabling diseases with a poor outcome for loco-motoric function if left untreated. RA and SpA each affect ...
Nov 16, 2018
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118
Spondyloarthritis is one of the most common types of chronic joint inflammation, affecting nearly 1 to 2 percent of the Western population. Cytokine blockade of tumor necrosis factor (TNF), and more recently, Interleukin-17 ...
Jan 11, 2019
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209
Navigation in mammals including humans and rodents depends on specialized neural networks that encode the animal's location and trajectory in the environment, serving essentially as a GPS, findings that led to the 2014 Nobel ...
Aug 16, 2017
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18
Scientists at VIB and KU Leuven have shown that blocking the PHD1 oxygen sensor hinders the activation of p53, a transcription factor that aids colorectal cancer (CRC) cells in repairing themselves and thus resisting chemotherapy. ...
Aug 19, 2015
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16
