New clue to Parkinson's: Shape of key protein surprises researchers
A new study finds that a protein key to Parkinson's disease has likely been mischaracterized. The protein, alpha-synuclein, appears to have a radically different structure in healthy cells than previously thought, challenging ...
Medical research
Aug 14, 2011 |
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Of enzymes and aging: Tryptophan metabolism plays key role in aging and age-related neurological diseases
(Medical Xpress)—In the battle against aging and age-related neurological diseases such as Parkinson's and Alzheimer's, a key factor has long appeared to be the toxicity of proteins which tend to aggregate. ...
Medical research
Oct 05, 2012 |
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Curcumin shows promise in attacking Parkinson's disease
Curcumin, a compound found in the spice turmeric, is proving effective at preventing clumping of a protein involved in Parkinson's disease, says a Michigan State University researcher.
Parkinson's & Movement disorders
Mar 20, 2012 |
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Copper folds protein into precursors of Parkinson's plaques
Researchers at North Carolina State University have figured out how copper induces misfolding in the protein associated with Parkinson's disease, leading to creation of the fibrillar plaques which characterize the disease. ...
Medical research
Jun 14, 2011 |
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Study reveals probable role of Parkinson's protein in healthy brain
(Medical Xpress)—Researchers at the Stanford University School of Medicine have exposed the possible function, in the healthy brain, of a mysterious molecule that has been strongly implicated in Parkinson's ...
Parkinson's & Movement disorders
May 01, 2013 |
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Rice opens new window on Parkinson's disease
(Medical Xpress)—Rice University scientists have discovered a new way to look inside living cells and see the insoluble fibrillar deposits associated with Parkinson's disease.
Parkinson's & Movement disorders
Dec 17, 2012 |
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Excess protein linked to development of Parkinson's disease
Researchers at the University of California, San Diego School of Medicine say overexpression of a protein called alpha-synuclein appears to disrupt vital recycling processes in neurons, starting with the ...
Parkinson's & Movement disorders
Feb 07, 2013 |
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Scientists identify 'clean-up' snafu that kills brain cells in Parkinson's disease
Researchers at Albert Einstein College of Medicine of Yeshiva University have discovered how the most common genetic mutations in familial Parkinson's disease damage brain cells. The study, which published online today in ...
Parkinson's & Movement disorders
Mar 03, 2013 |
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Defective cellular waste removal explains why Gaucher patients often develop Parkinson's disease
Gaucher disease causes debilitating and sometimes fatal neurodegeneration in early childhood. Recent studies have uncovered a link between the mutations responsible for Gaucher disease and an increased risk ...
Parkinson's & Movement disorders
May 23, 2013 |
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SUMO defeats protein aggregates that typify Parkinson's disease
A small protein called SUMO might prevent the protein aggregations that typify Parkinson's disease (PD), according to a new study in the July 11, 2011, issue of The Journal of Cell Biology.
Parkinson's & Movement disorders
Jul 11, 2011 |
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