Alzheimer's disease & dementia

Key signaling pathway in immune cells could be new Alzheimer's target

Inhibiting an important signaling pathway in brain-resident immune cells may calm brain inflammation and thereby slow the disease process in Alzheimer's and some other neurodegenerative diseases, suggests a study by Weill ...

Alzheimer's disease & dementia

Gram-negative bacteria may influence Alzheimer's disease pathology

For the first time, researchers have found higher levels of Gram-negative bacteria antigens in brain samples from late-onset Alzheimer's disease patients. Compared to controls, patients with Alzheimer's had much higher levels ...

Alzheimer's disease & dementia

Alzheimer protein's structure may explain its toxicity

Researchers at the University of Illinois at Chicago have determined the molecular structure of one of the proteins in the fine fibers of the brain plaques that are a hallmark of Alzheimer's disease. This molecule, called ...

Neuroscience

New findings contradict dominant theory in Alzheimer's disease

For decades the amyloid hypothesis has dominated the research field in Alzheimer's disease. The theory describes how an increase in secreted beta-amyloid peptides leads to the formation of plaques, toxic clusters of damaged ...

Alzheimer's disease & dementia

Natural plant compound prevents Alzheimer's disease in mice

(Medical Xpress)—A chemical that's found in fruits and vegetables from strawberries to cucumbers appears to stop memory loss that accompanies Alzheimer's disease in mice, scientists at the Salk Institute for Biological ...

Alzheimer's disease & dementia

Biomarker may predict early Alzheimer's disease

Researchers at Sanford Burnham Prebys Medical Discovery Institute (SBP) have identified a peptide that could lead to the early detection of Alzheimer's disease (AD). The discovery, published in Nature Communications, may ...

Alzheimer's disease & dementia

Artificial intelligence tool vastly scales up Alzheimer's research

Researchers at UC Davis and UC San Francisco have found a way to teach a computer to precisely detect one of the hallmarks of Alzheimer's disease in human brain tissue, delivering a proof of concept for a machine-learning ...

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