BRAF inhibitor treatment causes melanoma cells to shift how they produce energy
A multi-institutional study has revealed that BRAF-positive metastatic malignant melanomas develop resistance to treatment with drugs targeting the BRAF/MEK growth pathway through a major change in metabolism. The findings, ...
Cancer
Mar 08, 2013 |
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Cancer-promoting protein found to also suppress cell growth
Some cellular proteins have multiple, and occasionally opposing, functions. Professor Adrian Krainer [link: Faculty profile] and colleagues at Cold Spring Harbor Laboratory demonstrate in a paper published online today in ...
Medical research
Mar 07, 2013 |
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Comparing combination therapies for advanced head and neck cancer shows no improvement
Locally advanced squamous cell carcinoma of the head and neck is a potentially curable disease in nearly every patient at the time of diagnosis, yet despite the most aggressive efforts, up to 30-50 percent ...
Cancer
Mar 07, 2013 |
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Changing shape makes chemotherapy drugs better at targeting cancer cells
(Medical Xpress)—Bioengineering researchers at University of California, Santa Barbara have found that changing the shape of chemotherapy drug nanoparticles from spherical to rod-shaped made them up to ...
Cancer
Feb 27, 2013 |
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Cell sugar concentrations affect hyaluronan production and cancer growth
According to a recent University of Eastern Finland (UEF) study, elevated cell sugar concentrations increase the production of hyaluronan which, in turn, promotes cancer growth. Regulating the production ...
Cancer
Feb 27, 2013 |
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Ыtudy documents head and neck cancer molecular tumor subtypes
Head and neck squamous cell carcinoma (HNSCC) is the seventh most common form of cancer in the United States, but other than an association with the human papillomavirus, no validated molecular profile of ...
Cancer
Feb 22, 2013 |
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New drug combination could prevent head and neck cancer in high-risk patients
(Medical Xpress)—A new drug combination shows promise in reducing the risk for patients with advanced oral precancerous lesions to develop squamous cell carcinoma of the head and neck. The results of the study, which included ...
Cancer
Feb 19, 2013 |
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Pathway controlling cell growth revealed
A Melbourne-based research team has discovered a genetic defect that can halt cell growth and force cells into a death-evading survival state.
Cancer
Feb 18, 2013 |
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Novel designed molecules could stop colon cancer metastasis
A Basque research consortium has managed to stop the development of colon cancer and its liver metastasis in an experimental model using mice. This breakthrough, which could open new avenues for the future treatment of these ...
Cancer
Feb 14, 2013 |
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Key molecule suppresses growth of cancerous liver tumors, study finds
(Medical Xpress)—A molecule already implicated in a number of diverse cellular functions can suppress the growth of tumors in the liver, a Mayo Clinic Cancer Center study has found. Its name is IQGAP1, and when the molecule ...
Cancer
Feb 13, 2013 |
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Emerging cancer drugs may drive bone tumors
Cancer drugs should kill tumors, not encourage their spread. But new evidence suggests that an otherwise promising class of drugs may actually increase the risk of tumors spreading to bone, according to researchers ...
Cancer
Feb 13, 2013 |
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Protein that represses critical checkpoint protein for cellular growth helps drive tumor development
(Medical Xpress)—One of the hallmarks of cancer is unchecked cellular growth. Fortunately, our cells contain a number of tumor suppressor proteins, including the cell cycle regulator p21, to keep cell growth ...
Cancer
Feb 13, 2013 |
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New details on the molecular machinery of cancer
Researchers with Lawrence Berkeley National Laboratory (Berkeley Lab) and the University of California (UC) Berkeley have provided important new details into the activation of the epidermal growth factor ...
Cancer
Feb 11, 2013 |
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Some cancer mutations slow tumor growth
A typical cancer cell has thousands of mutations scattered throughout its genome and hundreds of mutated genes. However, only a handful of those genes, known as drivers, are responsible for cancerous traits ...
Cancer
Feb 04, 2013 |
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Researchers reveal mechanism to halt cancer cell growth, discover potential therapy
University of Pittsburgh Cancer Institute (UPCI) researchers have uncovered a technique to halt the growth of cancer cells, a discovery that led them to a potential new anti-cancer therapy.
Cancer
Feb 04, 2013 |
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