Genetics

Tumor suppressor mutations alone don't explain deadly cancer

Although mutations in a gene dubbed "the guardian of the genome" are widely recognized as being associated with more aggressive forms of cancer, researchers at the University of California, San Diego School of Medicine have ...

Medical research

Defective DNA damage repair leads to chaos in the genome

Scientists at the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) have now found a cause for frequent catastrophic events in the genetic material of cancer cells that have only been known for a few ...

Genetics

Researchers create DNA repair map of the entire human genome

When the common chemotherapy drugs cisplatin or oxaliplatin hit cancer cells, they damage DNA so that the cells can't replicate. But the cells have ways to repair the DNA. The cancer drugs aren't as effective as patients ...

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