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Twin epidemics: HIV and Hepatitis C in the urban Northeast

A new Yale study looks at the scope and consequences of a burgeoning health problem in the cities of the U.S. Northeast: concurrent infection with both HIV and Hepatitis C (HCV). The study appears online ...

HIV & AIDS created May 17, 2013 | popularity not rated yet | comments 0

Excessive soda can mimic illicit drug use effects on teeth

(HealthDay)—Manifestation of dental erosion caused by illicit drug use or excessive soda consumption needs to be distinguished from dental caries, according to case studies published in the March/April ...

Dentistry created May 13, 2013 | popularity 5 / 5 (1) | comments 0

Cocaine vaccine passes key testing hurdle

Researchers at Weill Cornell Medical College have successfully tested their novel anti-cocaine vaccine in primates, bringing them closer to launching human clinical trials. Their study, published online by the journal Neuropsychopharmacology, used a ...

Psychology & Psychiatry created May 10, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Mephedrone boosts illegal drug use

Experienced clubbers are more likely to add the former 'legal high' mephedrone to their drug repertoires rather than use it to replace popular established club drugs such as ecstasy and cocaine, according to new research ...

Addiction created Apr 23, 2013 | popularity 4 / 5 (1) | comments 1

Researchers identify pathway that may protect against cocaine addiction

(Medical Xpress)—A study by researchers at the National Institutes of Health gives insight into changes in the reward circuitry of the brain that may provide resistance against cocaine addiction. Scientists ...

Neuroscience created Apr 16, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Resetting addicted brain: Laser light zaps away cocaine addiction

By stimulating one part of the brain with laser light, researchers at the National Institutes of Health (NIH) and the Ernest Gallo Clinic and Research Center at UC San Francisco (UCSF) have shown that they ...

Neuroscience created Apr 03, 2013 | popularity 5 / 5 (11) | comments 7 | with audio podcast

Researcher study the dangerous effects of cocaine on HIV patients

Cocaine, already a damaging drug for those with healthy immune systems, can be lethal for those living with human immunodeficiency virus (HIV). Mudit Tyagi, Ph.D., assistant professor of medicine at the George Washington ...

HIV & AIDS created Mar 21, 2013 | popularity not rated yet | comments 0

Discovery could yield treatment for cocaine addicts

Scientists have discovered a molecular process in the brain triggered by cocaine use that could provide a target for treatments to prevent or reverse addiction to the drug.

Neuroscience created Mar 15, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Fall in heroin and crack use as drugs lose appeal, particularly for the young

(Medical Xpress)—The number of heroin and crack cocaine users in England has fallen below 300,000 for the first time.

Addiction created Mar 07, 2013 | popularity not rated yet | comments 0

Research pinpoints, prevents stress-induced drug relapse in rats

All too often, stress turns addiction recovery into relapse, but years of basic brain research have provided scientists with insight that might allow them develop a medicine to help. A new study in the journal Neuron pinpoi ...

Neuroscience created Mar 06, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Can qigong reduce cocaine cravings in early addiction recovery?

Cocaine is one of the most addictive drugs of abuse. Few effective treatments are available to help control cravings and withdrawal symptoms among individuals undergoing therapy to overcome cocaine abuse. ...

Addiction created Feb 25, 2013 | popularity not rated yet | comments 0

Study of cocaine addiction reveals targets for treatment

Scientists at UC Santa Barbara are researching cocaine addiction, part of a widespread problem, which, along with other addictions, costs billions of dollars in damage to individuals, families, and society.

Neuroscience created Feb 13, 2013 | popularity not rated yet | comments 0 | with audio podcast

Disulfiram: New support for an old addiction drug

Disulfiram was the first medication approved for the treatment of alcoholism over 50 years ago. It works, at least in part, by preventing the metabolism of an alcohol by-product, acetaldehyde. High levels of acetaldehyde ...

Psychology & Psychiatry created Jan 31, 2013 | popularity 5 / 5 (1) | comments 0

Scientists find gene interactions that make cocaine abuse death eight times more likely

Scientists have identified genetic circumstances under which common mutations on two genes interact in the presence of cocaine to produce a nearly eight-fold increased risk of death as a result of abusing the drug.

Genetics created Jan 22, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Children and siblings of deployed military more likely to use drugs

Youth with a deployed military parent or sibling use drugs and alcohol at a higher rate than their peers, finds a new study in American Journal of Preventive Medicine.

Health created Jan 18, 2013 | popularity 5 / 5 (1) | comments 0

Cocaine

Cocaine (benzoylmethylecgonine) is a crystalline tropane alkaloid that is obtained from the leaves of the coca plant. The name comes from "coca" in addition to the alkaloid suffix -ine, forming cocaine. It is both a stimulant of the central nervous system and an appetite suppressant. Specifically, it is a dopamine reuptake inhibitor, a norepinephrine reuptake inhibitor and a serotonin reuptake inhibitor, which mediates functionality of such as an exogenous DAT ligand. Because of the way it affects the mesolimbic reward pathway, cocaine is addictive.

Its possession, cultivation, and distribution are illegal for non-medicinal and non-government sanctioned purposes in virtually all parts of the world. Although its free commercialization is illegal and has been severely penalized in virtually all countries, its use worldwide remains widespread in many social, cultural, and personal settings.

For more information about Cocaine, read the full article at Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.

Related topics: brain , drug , neurons