Collagen is a building block that can be hierarchically assembled into diverse morphological structures that are dynamically adaptive in response to external cues. Materials scientists have limited capabilities of guiding ...
We may have been taught that milk does a body good, but when it comes to the ability of our tendons and ligaments to withstand the stresses of walking, running and injury, Secreted Protein Acidic and Rich in Cysteine (SPARC) ...
A team of researchers from Carnegie Mellon University has published a paper in Science that details a new technique allowing anyone to 3-D bioprint tissue scaffolds out of collagen, the major structural protein in the human ...
Aug 1, 2019
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Researchers at the Center for Genomic Regulation in Barcelona and the University of Cologne in Germany have developed a new experimental strategy to tackle scarring and fibrosis. Experiments with patient-derived human cells ...
Apr 24, 2024
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Combined exposure of the skin to cigarette smoke and UV rays could lead to faster premature aging, according to a study by Université Laval and the Centre de recherche du CHU de Québec-Université Laval.
Feb 27, 2024
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Disrupted function of "cleaning cells" in the body may help to explain why some people with obesity develop type 2 diabetes, while others do not. A study from the University of Gothenburg describes this newly discovered mechanism.
Feb 2, 2024
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Researchers have generated induced pluripotent stem cell (iPSC)-derived kidney organoids to model Alport syndrome caused by a mutation in the COL4A5 gene and have demonstrated the utility of a chemical chaperone to rescue ...
Oct 18, 2023
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Chronic inflammation of the middle ear can cause several problems and complications that can affect a person's hearing and balance. One such problem is the formation of a cholesteatoma, which is an abnormal collection of ...
Aug 3, 2023
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A team led by UT Southwestern Medical Center researchers has discovered a protein that appears to be pivotal for traumatic heterotopic ossification (HO), a condition in which bone forms in muscles, tendons, and other soft ...
Apr 18, 2023
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In the 1835 Hans Christian Andersen fairy tale "The Princess and the Pea," a princess is deemed authentic because of her sensitivity to a pea placed under 20 mattresses on her bed. New research from the McKelvey School of ...
Apr 12, 2023
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Collagen /ˈkɒlədʒɨn/ is a group of naturally occurring proteins found in animals, especially in the flesh and connective tissues of mammals. It is the main component of connective tissue, and is the most abundant protein in mammals, making up about 25% to 35% of the whole-body protein content. Collagen, in the form of elongated fibrils, is mostly found in fibrous tissues such as tendon, ligament and skin, and is also abundant in cornea, cartilage, bone, blood vessels, the gut, and intervertebral disc. The fibroblast is the most common cell which creates collagen.
In muscle tissue, it serves as a major component of the endomysium. Collagen constitutes one to two percent of muscle tissue, and accounts for 6% of the weight of strong, tendinous muscles. Gelatin, which is used in food and industry, is collagen that has been irreversibly hydrolyzed.
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