Infertility can have genetic causes, but pinpointing the culprit mutations is difficult because fertility and reproduction are controlled by many genes. These genes also carry many harmless but suspicious mutations in different ...
Aug 25, 2023
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One of the main features of Alzheimer's disease is that the β-amyloid peptide, a molecule found inside neurons that has many diverse functions, begins to fold incorrectly and accumulates. This process, which ends up causing ...
Dec 21, 2022
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(Medical Xpress)—Researchers from the Wellcome Trust Sanger Institute's cancer genome project have developed a computer model to identify the fingerprints of DNA-damaging processes that drive cancer development. Armed with ...
Jan 11, 2013
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Covalently closed circular RNAs (circRNAs) are produced by precursor mRNA back-splicing the exons of thousands of genes in eukaryotes. They are generally expressed at low levels and often exhibit cell-type-specific and tissue-specific ...
Apr 26, 2019
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Mycobacterium tuberculosis (Mtb) is the pathogen that causes tuberculosis (TB), the world's deadliest infectious disease. Mtb is so successful and harmful because it can adapt to different conditions inside our bodies, allowing ...
Aug 8, 2023
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New research is revealing how red blood cells are made and how the body regulates the amount of haemoglobin that is packaged in red blood cells at any time. Genomic analysis techniques have doubled the number of genetic regions ...
Dec 5, 2012
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February 13, 2013 – EcoHealth Alliance, the nonprofit organization that focuses on local conservation and global health issues, announced new research focused on the rapid identification of disease outbreaks in the peer ...
Feb 14, 2013
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Bacterial DNA may integrate into the human genome more readily in tumors than in normal human tissue, according to a new study from the University of Maryland School of Medicine's Institute for Genome Sciences. Researchers ...
Jun 20, 2013
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A tumor is not a uniform mass of identical cells. However, teasing apart genetic heterogeneity within a biopsied tumor can be difficult. Researchers often fail to tell the difference between a rare variant in a DNA dataset ...
Apr 24, 2013
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More than 10% of older adults develop somatic (non-inherited) mutations in blood stem cells that can trigger explosive, clonal expansions of abnormal cells, increasing the risk for blood cancer and cardiovascular disease.
Feb 8, 2023
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