News tagged with dendritic cells

Related topics: cells , white blood cells , immune response , immune system , immune cells

Shining a new light on the immune system

Scientists at the University of St Andrews have developed a revolutionary method of identifying cells of the immune system with "molecular fingerprints" which could pave the way for the rapid detection of ...

May 21, 2015
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Macrophages as T-cell primers

New work by Ludwig-Maximilians-Universitaet (LMU) in Munich researchers demonstrates that macrophages can effectively substitute for so-called dendritic cells as primers of T-cell-dependent immune responses. ...

Apr 15, 2015
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Dendritic cell

Dendritic cells (DCs) are immune cells that form part of the mammalian immune system. Their main function is to process antigen material and present it on the surface to other cells of the immune system, thus functioning as antigen-presenting cells.

Dendritic cells are present in small quantities in tissues that are in contact with the external environment, mainly the skin (where there is a specialized dendritic cell type called Langerhans cells) and the inner lining of the nose, lungs, stomach and intestines. They can also be found in an immature state in the blood. Once activated, they migrate to the lymphoid tissues where they interact with T cells and B cells to initiate and shape the adaptive immune response. At certain development stages they grow branched projections, the dendrites, that give the cell its name. However, these do not have any special relation with neurons, which also possess similar appendages. Immature dendritic cells are also called veiled cells, in which case they possess large cytoplasmic 'veils' rather than dendrites.

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