Metabolites called nucleotides are the building blocks of DNA and can impact cancer's sensitivity or resistance to chemotherapy and radiation in brain cancer. Findings from researchers at the University of Michigan Health ...
Nov 2, 2023
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A surprising mechanism that makes some cancers treatment-resistant has been discovered by Weill Cornell Medicine and NewYork-Presbyterian investigators. The mechanism, which involves the shuttling of messenger RNAs (mRNAs) ...
Nov 2, 2023
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Cancer treatment can rob childbearing-age women of fertility, but new research has uncloaked how the body's own traitor protein conspires with chemo and other harsh therapies against the ovaries' primordial follicles, home ...
Three decades after discoveries linking mutations in the BRCA1 gene to breast and ovarian cancer susceptibility, research led by Mays Cancer Center at The University of Texas Health Science Center at San Antonio (UT Health ...
Oct 6, 2023
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The National Institutes of Health is releasing a comprehensive dataset that standardizes genomic, proteomic, imaging, and clinical data from individual studies of more than 1,000 tumors across 10 cancer types. Researchers ...
Aug 14, 2023
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You likely know someone who seems to age slowly, appearing years younger than their birth date suggests. And you likely have seen the opposite—someone whose body and mind seem much more ravaged by time than others. Why ...
Jul 7, 2023
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In a new paper published today in Nature, researchers at the Francis Crick Institute have outlined the structure and function of a protein complex that is required to repair damaged DNA and protect against cancer.
Jun 21, 2023
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A new research paper titled "Key elements of cellular senescence involve transcriptional repression of mitotic and DNA repair genes through the p53-p16/RB-E2F-DREAM complex" has been published in Aging.
Jun 13, 2023
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A new research paper titled "LP-284, a small molecule acylfulvene, exerts potent antitumor activity in preclinical non-Hodgkin's lymphoma models and in cells deficient in DNA damage repair" has been published in Oncotarget.
Jun 12, 2023
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Researchers from Dana-Farber Cancer Institute, Brigham and Women's Hospital, and Medical University of Lodz have found a way to detect increased cancer risk associated with BRCA1 and BRCA2 mutations without genetic sequencing, ...
Jun 8, 2023
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