News tagged with estrogen receptor
Study reveals new mechanism for estrogen suppression of liver lipid synthesis
By discovering the new mechanism by which estrogen suppresses lipid synthesis in the liver, UC Irvine endocrinologists have revealed a potential new approach toward treating certain liver diseases.
Medical research
10 hours ago |
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Researchers identify new pathway, enhancing tamoxifen to tame aggressive breast cancer
Tamoxifen is a time-honored breast cancer drug used to treat millions of women with early-stage and less-aggressive disease, and now a University of Rochester Medical Center team has shown how to exploit tamoxifen's secondary ...
Cancer
Apr 23, 2013 |
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Cold winters freezing out breast cancer treatment
For women diagnosed with a form of breast cancer known as estrogen receptor positive (ER+) breast cancer, tamoxifen is an essential drug used in the treatment and prevention of recurring breast cancer. Currently, tamoxifen ...
Cancer
Apr 18, 2013 |
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Polymorphism in estrogen receptor alpha linked to back pain
(HealthDay)—For women with degenerative spondylolisthesis (DS), polymorphisms in the estrogen receptor α (ERα) are associated with back pain intensity, according to a study published in the April issue ...
Diseases, Conditions, Syndromes
Apr 11, 2013 |
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Studies show increasing evidence that androgen drives breast cancer
Estrogen and progesterone receptors, and the gene HER2 – these are the big three markers and/or targets in breast cancer. Evidence presented at the AACR Annual Meeting 2013 adds a fourth: androgen receptors.
Cancer
Apr 10, 2013 |
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Paragazole excels in preclinical models of triple-negative breast cancer
Breast cancers that lack estrogen receptors are more difficult to treat than ER+ cancers. Research presented at the AACR Annual Meeting 2013 demonstrates an investigational drug, Paragazole, that makes triple-negative ...
Cancer
Apr 08, 2013 |
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New DNA sequences hone in on breast, ovarian cancer risk
Researchers at Mayo Clinic Cancer Center have identified new DNA sequences associated with breast cancer—the most common cancer among women, with an average risk of developing the disease of 10 percent—and ovarian cancer, ...
Cancer
Mar 27, 2013 |
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Estrogen may improve pathway-selective insulin resistance
(HealthDay)—Estrogen treatment at the time of surgical menopause may reverse aspects of pathway-selective insulin resistance in the liver associated with a high-fat diet (HFD) in mice by promoting insulin ...
Diabetes
Feb 14, 2013 |
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BPA substitute could spell trouble: Experiments show bisphenol S also disrupts hormone activity
A few years ago, manufacturers of water bottles, food containers, and baby products had a big problem. A key ingredient of the plastics they used to make their merchandise, an organic compound called bisphenol A, had been ...
Health
Jan 22, 2013 |
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Ovarian cancer rates declining in breast cancer survivors
(HealthDay)—Primary ovarian cancer incidence is declining in the United States, both among the general population and among breast cancer survivors, according to research published online Jan. 2 in the ...
Cancer
Jan 08, 2013 |
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Women with higher carotenoid levels have reduced risk of breast cancer
Women with higher circulating carotenoid levels are at a reduced risk of breast cancer according to a study published December 6 in the Journal of the National Cancer Institute
Cancer
Dec 06, 2012 |
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10 years of tamoxifen better than 5, study reports
(HealthDay) —Taking the breast cancer drug tamoxifen for a decade, instead of the standard five years, further reduces the long-term chances of recurrence and risk of dying from the disease, new British ...
Cancer
Dec 05, 2012 |
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SABCS: Extending tamoxifen to 10 years beneficial in breast CA
(HealthDay)—For women with estrogen receptor (ER)-positive early breast cancer, continuing tamoxifen to 10 years correlates with reduced risk of recurrence and lower breast cancer-specific and overall mortality, ...
Cancer
Dec 05, 2012 |
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New finding gives clues for overcoming tamoxifen-resistant breast cancer
(Medical Xpress)—A University of Cincinnati (UC) cancer biology team reports breakthrough findings about specific cellular mechanisms that may help overcome endocrine (hormone) therapy-resistance in patients ...
Cancer
Nov 02, 2012 |
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Study shows breastfeeding reduced risk for ER/PR-negative breast cancer
Breast-feeding reduces the risk for estrogen receptor-negative and progesterone receptor-negative breast cancer, according to a study conducted at Columbia University's Mailman School of Public Health. Researchers examined ...
Cancer
Oct 18, 2012 |
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Estrogen receptor
Estrogen receptor refers to a group of receptors that are activated by the hormone 17β-estradiol (estrogen). Two types of estrogen receptor exist: ER which is a member of the nuclear hormone family of intracellular receptors and the estrogen G protein coupled receptor GPR30 (GPER), which is a G-protein coupled receptor. This article refers to the nuclear hormone receptor ER.
The main function of the estrogen receptor is as a DNA binding transcription factor that regulates gene expression. However, the estrogen receptor has additional functions independent of DNA binding.
For more information about Estrogen receptor, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
