Staking out unknown genomic territory
Scientists have long known that the human genome is incredibly complex. However, after almost 10 years of hard work, a team of more than 400 scientists at 32 research institutions worldwide has finally made ...
Genetics
Jan 04, 2013 |
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Study suggests gene variation may shape bladder cancer treatment
(Medical Xpress)—Patients who have inherited a specific common genetic variant develop bladder cancer tumors that strongly express a protein known as prostate stem cell antigen (PSCA), which is also expressed in many pancreatic ...
Cancer
Dec 27, 2012 |
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Monkey see, monkey do: Visual feedback is necessary for imitating facial expressions
(Medical Xpress)—Research using new technology shows that our ability to imitate facial expressions depends on learning that occurs through visual feedback.
Psychology & Psychiatry
Dec 27, 2012 |
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The X factor in liver metabolism
After you eat, your liver switches from producing glucose to storing it. At the same time, a cellular signaling pathway known as the unfolded protein response (UPR) is transiently activated, but it is not clear how this pathway ...
Medical research
Dec 21, 2012 |
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Research pinpoints key gene for regenerating cells after heart attack
UT Southwestern Medical Center researchers have pinpointed a molecular mechanism needed to unleash the heart's ability to regenerate, a critical step toward developing eventual therapies for damage suffered following a heart ...
Medical research
Dec 20, 2012 |
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Protein kinase Akt identified as arbiter of cancer stem cell fate, paper reports
(Medical Xpress)—The protein kinase Akt is a key regulator of cell growth, proliferation, metabolism, survival, and death. New work on Akt's role in cancer stem cell biology from the lab of senior author ...
Cancer
Dec 20, 2012 |
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Brake on nerve cell activity after seizures discovered: Gene expression initiates protective electrical response
Given that epilepsy impacts more than 2 million Americans, there is a pressing need for new therapies to prevent this disabling neurological disorder. New findings from the neuroscience laboratory of Mark ...
Neuroscience
Dec 19, 2012 |
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Cancer study overturns current thinking about gene activation
(Medical Xpress)—A new Australian study led by Professor Susan Clark from Sydney's Garvan Institute of Medical Research shows that large regions of the genome – amounting to roughly 2% – are epigenetically activated ...
Cancer
Dec 18, 2012 |
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Researchers discover how hepatitis C virus reprograms human liver cells
Hepatitis C virus has evolved to invade and hijack the basic machinery of the human liver cell to ensure its survival and spread. Researchers at the University of North have discovered how hepatitis C binds ...
Diseases, Conditions, Syndromes
Dec 18, 2012 |
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Harnessing the ID in glioma
Gliomas are the most common form of brain tumor. They are highly aggressive and effective treatments are not currently available. The tumors contain glioma initiating cells (GICs), a population that is highly similar to neural ...
Cancer
Dec 17, 2012 |
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PR+ cells add prognostic value in luminal A breast cancer
(HealthDay)—Semiquantitative immunohistochemical expression of progesterone receptor-positive tumor cells improves prediction of survival within luminal A breast cancers, according to a study published ...
Cancer
Dec 17, 2012 |
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Resistance to cocaine addiction may be passed down from father to son, study shows
Research from the Perelman School of Medicine at the University of Pennsylvania and Massachusetts General Hospital (MGH) reveals that sons of male rats exposed to cocaine are resistant to the rewarding effects of the drug, ...
Neuroscience
Dec 16, 2012 |
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Predictors of cancer disease progression improve patient selection for metastasis-directed therapy
Tumor metastasis, the ability of cancer cells to migrate from their tissue of origin and colonize elsewhere in the body, accounts for over 90% of cancer deaths. When patients die from cancer, it is usually caused by distant ...
Cancer
Dec 11, 2012 |
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Study finds epigenetics, not genetics, underlies homosexuality
Epigenetics – how gene expression is regulated by temporary switches, called epi-marks – appears to be a critical and overlooked factor contributing to the long-standing puzzle of why homosexuality occurs.
Genetics
Dec 11, 2012 |
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A better early blood test for autism: Genetic signatures point to disrupted neuro-immune pathways
(Medical Xpress)—Researchers at Boston Children's Hospital have developed a blood test for autism spectrum disorders (ASDs) that outperforms existing genetic tests, while presenting evidence that abnormal ...
Autism spectrum disorders
Dec 10, 2012 |
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