A gene therapy approach to treating the progressive muscle wasting disorder Duchenne muscular dystrophy (DMD) that does not replace the mutated DMD gene but instead delivers the gene for ITGA7, a protein in skeletal muscle, ...
Sep 29, 2015
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Gene transfer therapy aimed at correcting an enzyme abnormality involved in myocardial contraction and relaxation did not improve outcomes in heart failure patients with reduced ejection fraction, results of the CUPID 2 study ...
Sep 1, 2015
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Viruses often get bad press. Likened to Trojan horses they are often associated with disease. But, it is precisely because of their infectious nature that they can potentially be used as gene vectors - which are vehicles ...
Jun 24, 2014
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Cancer immunotherapy can successfully use the body's own immune system to kill tumor cells. But some current approaches to stimulate an antitumor immune response are short-lived, with limited clinical effectiveness. A new ...
Oct 9, 2013
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The receptor used by baculovirus to enter and interact with human cells has been identified. This syndecan–1 receptor was identified for the first time in a recent collaborative study carried out by the University of Eastern ...
Sep 27, 2013
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European scientists have made a major breakthrough in the treatment of inherited retinal diseases.
Jun 20, 2013
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Stent angioplasty saves lives, but there often are side effects and complications related to the procedure, such as arterial restenosis and thrombosis. In the June 2013 issue of The FASEB Journal, however, scientists report ...
May 30, 2013
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Nine of twelve leukemia patients who received infusions of their own T cells after the cells had been genetically engineered to attack the patients' tumors responded to the therapy, which was pioneered by scientists in the ...
Dec 10, 2012
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Investigators at Nationwide Children's Hospital have identified a mouse model that could help evaluate the risk that viral vectors used in gene therapy might promote tumor formation as a side-effect. The study appears in ...
Oct 26, 2012
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Japanese researchers developed a gene transfer technique that can "eliminate" a specific neural circuit in non-human primates for the first time in the world.
Jun 26, 2012
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