Study IDs key protein for cell death, offers way to kill cancer cells by forcing them into programmed-death pathway
When cells suffer too much DNA damage, they are usually forced to undergo programmed cell death, or apoptosis. However, cancer cells often ignore these signals, flourishing even after chemotherapy drugs have ...
Genetics
May 14, 2013 |
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Researchers discover that errors in RNA splicing lead to a class of neurological disorders
(Medical Xpress)—Researchers have found that missteps in a basic cellular process, RNA splicing, is the culprit behind a class of rare neurological disorders manifested by intellectual disability and stunted development.
Genetics
Mar 29, 2013 |
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Cell reprogramming during liver regeneration
During embryonic development, animals generate many different types of cells, each with a distinct function and identity.
Medical research
Mar 28, 2013 |
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Molecular master switch for pancreatic cancer identified, potential predictor of treatment outcome
A recently described master regulator protein may explain the development of aberrant cell growth in the pancreas spurred by inflammation
Cancer
Feb 12, 2013 |
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Researchers uncover novel role of BRCA1 in regulating the survival of skin stem cells
Our DNA, which stores our genetic information, is constantly exposed to damage. If not properly repaired, DNA damage can lead to cell death. This, in turn, can lead to tissue exhaustion and ageing, or induce mutations resulting ...
Cancer
Jan 03, 2013 |
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Study finds epigenetics, not genetics, underlies homosexuality
Epigenetics – how gene expression is regulated by temporary switches, called epi-marks – appears to be a critical and overlooked factor contributing to the long-standing puzzle of why homosexuality occurs.
Genetics
Dec 11, 2012 |
3.5 / 5 (4) |
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Study offers clues to cause of kids' brain tumors
(Medical Xpress)—Insights from a genetic condition that causes brain cancer are helping scientists better understand the most common type of brain tumor in children.
Genetics
Nov 16, 2012 |
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Unlocking the destiny of a cell
(Medical Xpress)— Scientists have discovered that breaking a biological signaling system in an embryo allows them to change the destiny of a cell. The findings could lead to new ways of making replacement ...
Genetics
Nov 01, 2012 |
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Researchers reveal how Trop2 protein drives tumor growth in prostate, other epithelial cancers
(Medical Xpress)—Researchers led by Tanya Stoyanova and Dr. Owen Witte of UCLA's Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research have determined how a protein known as Trop2 drives the growth ...
Cancer
Oct 16, 2012 |
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Protein found to regulate red blood cell size and number
The adult human circulatory system contains between 20 and 30 trillion red blood cells (RBCs), the precise size and number of which can vary from person to person. Some people may have fewer, but larger RBCs, while others ...
Genetics
Aug 28, 2012 |
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Study suggests patients should be screened before receiving vemurafenib
Different genetic mistakes driving skin cancer may affect how patients respond to the drug vemurafenib, providing grounds to screen people with melanoma skin cancer before treatment, a new study by Cancer Research UK scientists ...
Cancer
Aug 14, 2012 |
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In vitro study identifies potential combination therapy for breast cancer
A study conducted at Boston University School of Medicine (BUSM) demonstrates an effective combination therapy for breast cancer cells in vitro. The findings, published in the July 2012 issue of Anticancer Research, raise ...
Cancer
Jul 02, 2012 |
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MicroRNAs link the pathways that control growth during animal development and in disease
Cellular mechanisms that enable healthy growth can spiral out of control and give rise to cancer. For this reason, signal transduction pathways that underlie cell growth are tightly regulated, with multiple ...
Medical research
Jun 20, 2012 |
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Elimination of two ribosome subunits activates cell cycle control
Alterations in the formation of ribosomes (the elements of the cell where proteins are made) cause the induction of p53 protein and cell cycle disruption. This process is crucial to understand fundamental biological processes ...
Genetics
May 22, 2012 |
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The influence of the mother: Maternal epigenetic inheritance
(Medical Xpress) -- A study published in Genes and Development from scientists at the Friedrich Miescher Institute for Biomedical Research pinpoints the importance of maternal epigenetic influences during ...
Genetics
May 07, 2012 |
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